Chinese Academy of Sciences (CAS) - Department of Experimental Medical Science, Heidelberg University, Chinese Academy of Sciences (CAS) - Department of Experimental Medical Science, Chinese Academy of Sciences (CAS) - Institute of Neuroscience, Ningbo University - Zhejiang Provincial Key Laboratory of Pathological and Physiological Technology, Chinese Academy of Sciences (CAS) - Department of Experimental Medical Science, Chinese Academy of Sciences (CAS) - Department of Experimental Medical Science, Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province and Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province