Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, University of Angers - French Institute of Health and Medical Research (INSERM), University of Cambridge, Addenbrookes Hospital, Department of Psychiatry, University of Ioannina - Department of Hygiene and Epidemiology, Huazhong University of Science and Technology - Department of Occupational and Environmental Health, Harvard University - Genetics and Aging Research Unit, Capital Medical University - Department of Neurology, National University of Singapore (NUS) - Yong Loo Lin School of Medicine, National University of Singapore (NUS) - Yong Loo Lin School of Medicine, Third Military Medical University, Daping Hospital, Institute of Surgery Research, Department of Neurology, Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, Qingdao University - Department of Neurology, The Chinese University of Hong Kong (CUHK), Faculty of Medicine, Gerald Choa Neuroscience Centre, Qingdao University - Department of Neurology, Université Montpellier I, McGill University, University of Southern California and Université de Toulouse - WHO Collaborating Center for Frailty, Clinical and Geroscience Research, and Geriatric Training