Xavier Verdaguer

Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona)

Parc Científic de Barcelona

C/ Baldiri Reixac 10

Barcelona, 08028

Spain

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Scholarly Papers (1)

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Optimal Linker Length for Small Molecule PROTACs that Selectively Target P38α and P38β for Degradation

Number of pages: 50 Posted: 03 Jul 2019
Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona) and Barcelona Institute of Science and Technology (BIST) - Institute for Research in Biomedicine (IRB Barcelona)
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Abstract:

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Azide-alkyne click reaction, Cereblon, p38 MAPK, PROTAC linker optimization, Protein degradation, Thalidomide derivative