University of Duisburg-Essen - Department of Neurology, University of Duisburg-Essen - Department of Neurology, University Hospital Essen - Institute of Medical Informatics, Biometry und Epidemiology (IMIBE), University of Duisburg-Essen - University Hospital Essen, University of Duisburg-Essen - University Hospital Essen, University of Duisburg-Essen - Department of Neurology, Ludwig Maximilian University of Munich (LMU), University of Duisburg-Essen - University Hospital Essen, Helios-Klinikum Krefeld, Heinrich Heine University Dusseldorf - Faculty of Medicine, University Hospital Essen - Institute of Medical Informatics, Biometry und Epidemiology (IMIBE), University of Duisburg-Essen - University Hospital Essen, University of Duisburg-Essen - Department of Neurology and Independent