Fuying Gao

University of California, Los Angeles (UCLA)

405 Hilgard Avenue

Box 951361

Los Angeles, CA 90095

United States

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Scholarly Papers (1)

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AD-Linked TREM2 Mutation Induces Unique Microglial States Associated with Toxic Function in Tauopathy

CELL-D-19-01794
Number of pages: 68 Posted: 16 Jul 2019
University of California, San Francisco (UCSF), Gladstone Institute of Neurological Disease, Gladstone Institute of Neurological Disease, Massachusetts Institute of Technology (MIT), Gladstone Institute of Neurological Disease, Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center - Program for Computational and Systems Biology, Massachusetts Institute of Technology (MIT), Gladstone Institute of Neurological Disease, University of California, Los Angeles (UCLA), Gladstone Institute of Neurological Disease, Cornell University, Cornell University, Gladstone Institute of Neurological Disease, University of California, San Francisco (UCSF) - Gladstone Institute of Neurological Disease, University College London - Department of Molecular Neuroscience, University of California, Los Angeles (UCLA) - Department of Neurology, Massachusetts Institute of Technology (MIT) and Gladstone Institute of Neurological Disease
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Abstract:

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TREM2, R47H, microglia, inflammation, tauopathy, single-nuclei RNA-sequencing, Alzheimer's disease, memory impairment, synaptic function