Rovira i Virgili University - Critical Care Department URV/IISPV/CIBERES, Rovira i Virgili University - Critical Care Department URV/IISPV/CIBERES, Universidad de Las Palmas Gran Canaria, St James’s University Hospital, Hospital Parc Taulí, Rovira i Virgili University - Critical Care Department URV/IISPV/CIBERES, Universidad de la Sabana, Rovira i Virgili University - Critical Care Department URV/IISPV/CIBERES, University of Louisville - School of Medicine, Rovira i Virgili University - Critical Care Department URV/IISPV/CIBERES, Hospital Universitario Donostia, Vall d´Hebrón University Hospital, Hospital Universitario Son Llatzer, Hospital Clinic of Barcelona - Department of Infectious Diseases, Rovira i Virgili University - Critical Care Department URV/IISPV/CIBERES, Autonomous University of Barcelona - Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), University of Texas Health Science Center at San Antonio, University of Nottingham - School of Medicine, University of Barcelona - Faculty of Medicine and Independent