University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Institute of Cellular Medicine, University of Birmingham - Institute of Cancer and Genomic Sciences, Goethe University Frankfurt - Institute of Pharmaceutical Biology, University of Newcastle - Wolfson Childhood Cancer Research Centre, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Birmingham - Institute of Cancer and Genomic Sciences, University of Birmingham - Institute of Cancer and Genomic Sciences, University of Nottingham, University of Birmingham - Institute of Cancer and Genomic Sciences, Christian Albrechts University Kiel - Pediatric Hematology/Oncology, Cincinnati Children's Hospital Medical Center - Cancer and Blood Disease Institute, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, St James’s University Hospital - Haematological Malignancy Diagnostic Service, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of York - Epidemiology and Cancer Statistics Group, University of Birmingham - Institute of Cancer and Genomic Sciences, Illumina Cambridge Ltd., Illumina Cambridge Ltd., Charité - Universitätsmedizin Berlin - Department of Paediatric Oncology and Haematology, St. Anna Kinderkrebsforschung - Children's Cancer Research Institute, The Great North Children’s Hospital - Department of Paediatric Haematology and Oncology, University of Newcastle - Wolfson Childhood Cancer Research Centre, The Great North Children’s Hospital - Department of Paediatric Haematology and Oncology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, University of Newcastle - Institute of Cellular Medicine, University of Newcastle - Institute of Cellular Medicine, University of Newcastle - Institute of Cellular Medicine, Goethe University Frankfurt - Institute of Pharmaceutical Chemistry, University of Newcastle - Wolfson Childhood Cancer Research Centre, St James’s University Hospital - Haematological Malignancy Diagnostic Service, Christian Albrechts University Kiel - Pediatric Hematology/Oncology, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, University of Chicago - Section of Hematology/Oncology, University of Birmingham - Institute of Cancer and Genomic Sciences, Cincinnati Children's Hospital Medical Center - Cancer and Blood Disease Institute, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Newcastle - Wolfson Childhood Cancer Research Centre, University of Birmingham - Institute of Cancer and Genomic Sciences, Princess Maxima Center for Pediatric Oncology and University of Newcastle - Wolfson Childhood Cancer Research Centre