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Markku Varjosalo

University of Helsinki - Institute of Biotechnology

University of Helsinki - Systems Biology Research Group and Proteomics Unit

Finland

  • University of Helsinki - Systems Biology Research Group and Proteomics Unit

SCHOLARLY PAPERS

7

DOWNLOADS

316

TOTAL CITATIONS

0

Scholarly Papers (7)

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1.

Structure and Interactions of the Endogenous Human Commander Complex

Number of pages: 52 Posted: 29 Mar 2023
Saara Laulumaa, Esa-Pekka Kumpula, Juha T. Huiskonen and Markku Varjosalo
University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology and University of Helsinki - Institute of Biotechnology
Downloads 77 (823,616)

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Endogenous human Commander complex, Cryo-EM, Interaction proteomics, Structural BiologyEndosomal sorting:Intracellular trafficking, Ciliogenesis, Centrosome

2.

Physical and Functional Interactome Atlas of Human Receptor Tyrosine Kinases

Number of pages: 38 Posted: 24 Feb 2021
Kari Salokas, Tiina Öhman and Markku Varjosalo
University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology and University of Helsinki - Institute of Biotechnology
Downloads 56 (1,000,027)

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3.

Reduced Binding of Apolipoprotein E4 Isoform to Complement Factor H Promotes Amyloid-Β Induced Neuroinflammation in vitro and in vivo

Number of pages: 47 Posted: 14 Jul 2022
Larisa Chernyaeva, Giorgio Ratti, Laura Teirilä, Uni Rankka, Satoshi Fudo, Anssi Pelkonen, Paula Korhonen, Katarzyna Leskinen, Salla Keskitalo, Kari Salokas, Christina Gkolfinopoulou, Katrina E. Crompton, Markku Varjosalo, Tarja Malm, Ville Leinonen, Angelika Chroni, Päivi Saavalainen, Seppo Meri, Adam J.M. Wollman, Eija Nissilä and Karita Haapasalo
University of Helsinki - Department of Bacteriology and Immunology, Humanitas University, University of Helsinki - Department of Bacteriology and Immunology, University of Helsinki - Department of Bacteriology and Immunology, University of Helsinki - Department of Bacteriology and Immunology, University of Eastern Finland - A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland - A.I. Virtanen Institute for Molecular Sciences, University of Helsinki - Department of Bacteriology and Immunology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, NCSR "Demokritos" - Institute of Biosciences and Applications, Newcastle University - Biosciences Institute, University of Helsinki - Institute of Biotechnology, University of Eastern Finland - A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland - Institute of Clinical Medicine, NCSR "Demokritos" - Institute of Biosciences and Applications, University of Helsinki - Department of Bacteriology and Immunology, University of Helsinki - Department of Bacteriology and Immunology, Newcastle University - Biosciences Institute, University of Helsinki - Department of Bacteriology and Immunology and University of Helsinki - Department of Bacteriology and Immunology
Downloads 48 (1,086,013)

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Dementia, neurodegeneration, Neuroinflammation, Inflammation

4.

A Proteocistromic Atlas of Human Transcription Factors

Number of pages: 50 Posted: 30 Sep 2024
Zenglai Tan, Zixian Wang, Xiaonan Liu, Binjie Luo, Guowen Duan, Longguang Qin, Yuehong Yang, Shuangshuang Ma, Xiayun Yang, Qin Zhang, Aki Manninen, Markku Varjosalo, Gong-Hong Wei and Sneak Peek Administrator
University of Oulu, Fudan University, University of Helsinki - Institute of Biotechnology, University of Oulu, Fudan University, University of Oulu, University of Oulu, University of Oulu, University of Oulu, University of Oulu, University of Oulu, University of Helsinki - Institute of Biotechnology, Fudan University and Independent
Downloads 43 (1,196,171)

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Transcription factor, AP-MS, BioID, ChIP-seq, Proteocistromic, Allele-specific binding, TF pairs

5.

Novel Tumor Suppressor PTPRA Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

Number of pages: 50 Posted: 20 Aug 2019
Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Kaisa Lehti, Mart Saarma and Markku Varjosalo
University of Helsinki - Systems Biology Research Group and Proteomics Unit, University of Helsinki - Research Programs Unit, University of Helsinki - Institute of Biotechnology, University of Helsinki - Systems Biology Research Group and Proteomics Unit, University of Helsinki - Laboratory of Molecular Neuroscience, University of Helsinki - Research Programs Unit, University of Helsinki - Laboratory of Molecular Neuroscience and University of Helsinki - Institute of Biotechnology
Downloads 40 (1,183,237)

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Ras-MAPK growth signaling, substrate dephosphorylation, RET phosphosites, PTPase domain, cancer invasion, and regulation

6.

Examining the Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations

Number of pages: 34 Posted: 17 Mar 2023
Matias Kinnunen, Xiaonan Liu, Elina Niemelä, Tiina Öhman, Lisa Gawriyski, Kari Salokas, Salla Keskitalo and Markku Varjosalo
University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology and University of Helsinki - Institute of Biotechnology
Downloads 33 (1,277,121)

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oncofusions, cancer, signaling, Interactomics, proteomics, mass cytometry, Drug Discovery

7.

Cervical Lymphadenectomy Compromises Brain Lymphatic Clearance and Synaptic Proteostasis

Number of pages: 81 Posted: 18 Mar 2026
Zohaib Khan, Cristina Clement, Paula Roßmüller, Salli Antilla, Lincoln Sutherland, Rafi Kabarriti, Justina Shafik, Igor Smirnov, Angelo D’Alessandro, Monika Dzieciatkowska, Barbara Roda, Valentina Marassi, Wanxia Li Xai, Massimo Gadina, Allen Tannenbaum, Markku Varjosalo, Salla Keskitalo, Andras Piffko, Sounil Kundal, Zachary Gursky, Ralph Weichselbaum, Michael Prystowsky, Thomas Ow, Silvia Formenti, Helene Benveniste, Christian Sorg, Kari Alitalo, Benedikt Zott, Jonathan Kipnis and Laura Santambrogio
Cornell University - Weill Cornell Medicine, Cornell University - Weill Cornell Medicine, Technische Universität München (TUM), University of Helsinki - Wihuri Research Institute and Translational Cancer Medicine Program, Yeshiva University - Albert Einstein College of Medicine, Montefiore Medical Center, Yeshiva University - Albert Einstein College of Medicine, Washington University in St. Louis, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora - Department of Biochemistry and Molecular Genetics, University of Bologna, University of Bologna, Government of the United States of America - National Institutes of Health (NIH), Government of the United States of America - National Institutes of Health (NIH), State University of New York (SUNY), Stony Brook, University of Helsinki - Institute of Biotechnology, University of Helsinki - Institute of Biotechnology, University of Chicago, Yale University, Yale University, University of Chicago, Yeshiva University - Albert Einstein College of Medicine, Montefiore Medical Center, Cornell University - Weill Cornell Medicine, Yale University, Technische Universität München (TUM), University of Helsinki - Wihuri Research Institute and Translational Cancer Medicine Program, Technische Universität München (TUM), Washington University in St. Louis and Cornell University - Department of Radiation Oncology
Downloads 19 (1,470,786)

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cervical lymph nodeslymphdementiaprotein aggregation