Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, King’s College London - British Heart Foundation (BHF) Centre of Research Excellence, Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, Central South University - Center for Clinical Pharmacology, Central South University - Department of Dermatology, Central South University - Department of Dermatology, Central South University - Department of Social Medicine and Health Management, Central South University - Department of Social Medicine and Health Management, Central South University - Xiangya School of Public Health, Central South University - School of Materials Science and Engineering, Huazhong University of Science and Technology - Department of Occupational and Environmental Health, Peking University - College of Environmental Science and Engineering, Central South University - Center for Clinical Pharmacology and King’s College London - British Heart Foundation (BHF) Centre of Research Excellence