University of Oxford - Nuffield Department of Primary Care Health Sciences, Utrecht University - University Medical Center (Utrecht), University of Oxford - Department of Primary Care Health Services, Berry Consultants, LLC, University of Oxford - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford - Department of Primary Care Health Services, University of Antwerp, University of Southampton - Primary Care and Population Science, University of California, Los Angeles (UCLA) - Harbor-UCLA Medical Center, Medical University of Lodz, Via Roma Health Centre, Medical University of Bialystok, University of Crete - Clinic of Social and Family Medicine, Charles University in Prague, Research and Development Centre Södra Älvsborg, University of Antwerp, University of Copenhagen, Faculty of Health and Medical Sciences, Department of Public Health, University of Copenhagen, Faculty of Health and Medical Sciences, Department of Public Health, University of Oslo - Department of General Practice, University of Oslo - Department of General Practice, University of Basel - University Hospital Basel, University of Basel - University Hospital Basel, Drug Research Centre, JSC Mano Seimos Gydytojas, Université Cote d'Azur - Centre Hospitalier Universitaire de Nice, University of Southampton - Primary Care and Population Science, Health Research Board Primary Care Clinical Trial Network Ireland, Ghent University - Department of Public Health and Primary Care, Imperial College London - National Heart and Lung Institute, University of Amsterdam - Department of Medical Microbiology, University of Central Florida, University of Antwerp - Vaccine and Infectious Disease Institute, University of Antwerp - Vaccine and Infectious Disease Institute, University of Antwerp - Laboratory of Medical Microbiology and Utrecht University - University Medical Center (Utrecht)