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Gang Chen

Nantong University - Department of Occupational Medicine and Environmental Toxicology

China

  • Nantong University - Department of Occupational Medicine and Environmental Toxicology

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p62/SQSTM1 Accumulation Resulting from Degradation Inhibition and Transcriptional Activation is Essential in Silica Nanoparticle-Induced Pulmonary Inflammation Through NF-κB Activation

Number of pages: 34 Posted: 09 Sep 2019
Yifan Wu, Yang Jin, Tianyu Sun, Piaoyu Zhu, Jinlong Li, Qinglin Zhang, Xiaoke Wang, Yu Han, Junkang Jiang, Gang Chen and Xinyuan Zhao
Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - School of Pharmacy, Nanjing Medical University - Department of Gastroenterology, Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - Department of Occupational Medicine and Environmental Toxicology, Nantong University - Department of Occupational Medicine and Environmental Toxicology and Nantong University - Department of Occupational Medicine and Environmental Toxicology
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silica nanoparticle, pulmonary inflammation, p62 accumulation, autophagic flux blockade, transcriptional activation, Nrf2