Zhixun Dou

University of Pennsylvania - Department of Cell and Developmental Biology

3400 Civic Center Blvd

Philadelphia, PA 19104

United States

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Scholarly Papers (1)

1.

Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals

CELL-D-19-02609
Number of pages: 104 Posted: 02 Oct 2019
Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Harvard Medical School - Genetics Division, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department, Dovetail Genomics, Dovetail Genomics, Dovetail Genomics, University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, University of Washington - Division of Nephrology, University of Washington - Division of Nephrology, University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of California, Santa Cruz - Department of Biomolecular Engineering (BME), University of Pennsylvania - Department of Cell and Developmental Biology, University of Pennsylvania - Department of Cell and Developmental Biology, National Institutes of Health - Laboratory of Receptor Biology and Gene Expression, University of Washington - Division of Nephrology, Harvard Medical School - Genetics Division, Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research, Carnegie Mellon University - Computational Biology Department and Harvard Medical School - Paul F. Glenn Center for Biology of Aging Research
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Abstract:

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DNA damage, chromatin, aging, epigenetic clock, histone modification, RCM(Relocalization of Chromatin Modifiers)