Author Page for Nobuyuki Yamamoto

Radiotherapy-Free Pembrolizumab Combined with Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer with Pd-L1 TPS ≥50%: A Phase II Study (Evolution Trial: WJOG11819L)

Number of pages: 26 Posted: 23 Apr 2025

Akito Hata, Taira Ninomaru, Hideaki Okada, Yoshihito Kogure, Masahide Oki, Nobuyuki Katakami, Takashi Kijima, Toshihide Yokoyama, Hirotaka Matsumoto, Yuki Sato, Terufumi Kato, Shunichi Sugawara, Takeshi Sawada, Kenichi Yoshimura, Takashi Seto, Kazuhiko Nakagawa, Isamu Okamoto and Nobuyuki Yamamoto

Kobe Minimally Invasive Cancer Center, Kobe Minimally Invasive Cancer Center, Kobe Minimally Invasive Cancer Center, National Hospital Organization (NHO) - Department of Respiratory Medicine, National Hospital Organization (NHO) - Nagoya Medical Center, Takarazuka City Hospital, Hyogo Medical University, Kurashiki Central Hospital - Department of Respiratory Medicine, Hyogo Prefectural Amagasaki General Medical Center, Kobe City Medical Center General Hospital, Kanagawa Cancer Center, Sendai Kousei Hospital - Department of Pulmonary Medicine, Kyoto University, Nagoya City University, National Hospital Organization Kyushu Cancer Center, Kindai University, Kyushu University - Kyushu University Hospital and Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology

Downloads 116 (613,149)

Abstract:

2.

Phase III Study of Cisplatin Plus Pemetrexed versus Cisplatin Plus Vinorelbine for Completely Resected Stage II-IIIA Non-Squamous Non-Small-Cell Lung Cancer: The JIPANG Study

Number of pages: 108 Posted: 01 Oct 2019

Hirotsugu Kenmotsu, Nobuyuki Yamamoto, Takeharu Yamanaka, Katsuo Yoshiya, Toshiaki Takahashi, Tsuyoshi Ueno, Koichi Goto, Haruko Daga, Norihiko Ikeda, Kenji Sugio, Takashi Seto, Shinichi Toyooka, Hiroshi Date, Tetsuya Mitsudomi, Isamu Okamoto, Kohei Yokoi, Hideo Saka, Hiroaki Okamoto, Yuichi Takiguchi and Masahiro Tsuboi

Shizuoka Cancer Center - Division of Thoracic Oncology, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology, Yokohama City University, Niigata Cancer Center Hospital, Shizuoka Cancer Center - Division of Thoracic Oncology, National Hospital Organization Shikoku Cancer Center, National Cancer Center Hospital East, Osaka City General Hospital, Tokyo Medical University, Oita University, National Hospital Organization Kyushu Cancer Center, Okayama University, Kyoto University, Kindai University, Kyushu University, Nagoya University, National Hospital Organization (NHO) - Nagoya Medical Center, Yokohama Municipal Citizen's Hospital, Chiba University - Chiba University Hospital and National Cancer Center Hospital East

Downloads 61 (951,658)

Citation 1

Abstract:

3.

Efficacy and Safety of Carboplatin With Nab-Paclitaxel Versus Docetaxel in Elderly Patients with Squamous-Cell Lung Cancer (CAPITAL): A Randomized, Multicenter, Open-Label, Phase III Trial

Number of pages: 35 Posted: 17 May 2021

National Hospital Organization (NHO) - Department of Respiratory Medicine, Chiba University - Department of Respirology, National Hospital Organization (NHO) - Nagoya Medical Center, National Hospital Organization (NHO) - Nishisaitama-Chuo National Hospital, National Hospital Organization (NHO), Nagoya Medical Center, Clinical Research Center, Nagoya City University - Core Laboratory, National Hospital Organization - Department of Thoracic Oncology, Chiba University - Chiba University Hospital, Iizuka Hospital - Department of Respiratory Oncology, Tohoku University - Department of Palliative Medicine, Kansai Medical University - Kansai Medical University Hospital, Kyushu University, National Hospital Organization (NHO) - Department of Thoracic Oncology, Hokkaido University Hospital - Division of Laboratory and Transfusion Medicine, Nippon Medical School - Department of Pulmonary Medicine and Oncology, Yokohama City University - Department of Biostatistics, Nagoya University - Center for Advanced Medicine and Clinical Research, National Hospital Organization (NHO), Nagoya Medical Center, Clinical Research Center, Nippon Medical School - Department of Pulmonary Medicine and Oncology, National Hospital Organization Kyushu Cancer Center, National Hospital Organization Kyushu Cancer - Department of Thoracic Oncology,, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology and Nippon Medical School

Downloads 57 (989,921)

Abstract:

4.

Efficacy of pembrolizumab plus pemetrexed in older patients with non-squamous NSCLC according to PD-L1 expression status: Results from the CJLSG1901 study

Number of pages: 26 Posted: 16 Sep 2025

Yoshihito Kogure, Masahide Mori, Takashi Abe, Akiko M. Saito, Nobuyuki Yamamoto, Hideo Saka, Masashi Kondo, Satoshi Ikeda, Toshiyuki Harada, Aoi Hino, Satoru Miura, Yasuhiro Goto, Keiichi Fujiwara, Nobuyuki Katakami, Kaoru Kubota, Naohiko Murata and Hiroya Hashimoto

National Hospital Organization Nagoya Medical Center, National Hospital Organization (NHO) - Osaka Toneyama Medical Center, Ogaki Municipal Hospital, National Hospital Organization (NHO), Nagoya Medical Center, Clinical Research Center, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology, Matsunami General Hospital, Fujita Health University, Kanagawa Cardiovascular and Respiratory Center, Hokkaido University Hospital - Division of Laboratory and Transfusion Medicine, Chiba University, affiliation not provided to SSRN, Fujita Health University, affiliation not provided to SSRN, Takarazuka City Hospital, Nippon Medical School - Department of Pulmonary Medicine and Oncology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital and Nagoya City University - Core Laboratory

Downloads 50 (1,063,489)

Abstract:

5.

Durvalumab with Etoposide and Carboplatin for Patients with Extensive-Stage Small Cell Lung Cancer and Interstitial Lung Disease: A Multicenter, Open-Label Prospective Trial

Number of pages: 28 Posted: 05 Aug 2024

Wakayama Medical University, Wakayama Medical University, Tohoku University - Tohoku University Hospital, Tohoku University, Saiseikai Utsunomiya Hospital, Saiseikai Utsunomiya Hospital, Saiseikai Kumamoto Hospital, Saiseikai Kumamoto Hospital, Wakayama Medical University, Hyogo Medical University, Osaka International Cancer Institute, Sendai Kousei Hospital, Itami City Hospital, Chiba University - Chiba University Hospital, Kobe City Medical Center General Hospital, Kurashiki Central Hospital - Department of Respiratory Medicine, Kumamoto University - Kumamoto University Hospital, Kinki-chuo Chest Medical Center, Kobe Minimally Invasive Cancer Center, Hyogo Prefectural Amagasaki General Medical Center, affiliation not provided to SSRN and Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology

Downloads 49 (1,074,648)

Abstract:

6.

A Phase II Study (WJOG12819L) to Assess the Efficacy of Osimertinib in Patients with EGFR Mutation-Positive NSCLC in Whom Systemic Disease (T790M-Negative) Progressed after Treatment with First- Or Second-Generation EGFR TKIS and Platinum-Based Chemotherapy

Number of pages: 19 Posted: 04 Jan 2023

Masayuki Takeda, Mototsugu Shimokawa, Atsushi Nakamura, Kaname Nosaki, Yasutaka Watanabe, Terufumi Kato, Daisuke Hayakawa, Hiroshi Tanaka, Toshiaki Takahashi, Masahide Oki, Motoko Tachihara, Daichi Fujimoto, Hidetoshi Hayashi, Kakuhiro Yamaguchi, Shoichiro Yamamoto, Eiji Iwama, Koichi Azuma, Kazuo Hasegawa, Nobuyuki Yamamoto and Kazuhiko Nakagawa

Kindai University, Yamaguchi University, Sendai Kousei Hospital, National Cancer Center Hospital East, Saitama Cancer Center, Kanagawa Cancer Center, Juntendo University - Juntendo University Hospital, Niigata Cancer Center Hospital, Shizuoka Cancer Center, National Hospital Organization Nagoya Medical Center, Kobe University, Wakayama Medical University, Kindai University, Hiroshima University - Hiroshima University Hospital, Ehime University Graduate School of Medicine, Kyushu University - Kyushu University Hospital, Kurume University - Department of Internal Medicine, Japan Lung Cancer Alliance, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology and Kindai University

Downloads 42 (1,157,785)

Abstract:

7.

Longitudinal Analysis Reveals the Impact of Adjuvant Cytotoxic Chemotherapy in Egfr-Mutated Lung Cancer: A Combined Analysis of Phase Iii Studies

Number of pages: 36 Posted: 15 Nov 2024

Hiroaki Akamatsu, Tomomi Nishikawa, Yuriko Takeda, Toshihiro Misumi, Tadashi Aoki, Hiroyasu Shoda, Motohiro Yamashita, Noriaki Sakakura, Haruko Daga, Shunichi Sugawara, Kyoichi Okishio, Hirotsugu Kenmotsu, Nobuyuki Yamamoto, Hirohito Tada, Masahiro Tsuboi and Tetsuya Mitsudomi

Wakayama Medical University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Niigata Cancer Center Hospital, Hiroshima City Hiroshima Citizens Hospital, affiliation not provided to SSRN, Aichi Cancer Center, Osaka City General Hospital, Sendai Kousei Hospital - Department of Pulmonary Medicine, affiliation not provided to SSRN, Shizuoka Cancer Center - Division of Thoracic Oncology, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology, affiliation not provided to SSRN, National Cancer Center Hospital East - Department of Thoracic Surgery and affiliation not provided to SSRN

Downloads 40 (1,183,237)

Abstract:

8.

Biological Impact of Chemotherapy During Treatment with Egfr Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer Positive for Egfr Activating Mutations

Number of pages: 24 Posted: 11 Apr 2025

Eiji Iwama, Kazuko Sakai, Taishi Harada, Shintaro Kanda, Shunichi Sugawara, Toshihide Yokoyama, Hirokazu Taniguchi, Kaoru Tanaka, Ryo Toyozawa, Kenichi Koyama, Yoshitaka Zenke, Gen Kida, Yasuhiko Nishioka, Hiroshi Yokouchi, Masayuki Hirose, Kazuto Nishio, Nobuyuki Yamamoto, Yuichiro Ohe and Isamu Okamoto

Kyushu University - Kyushu University Hospital, Kindai University - Kindai University Hospital, affiliation not provided to SSRN, Shinshu University - Department of Hematology and Medical Oncology, Sendai Kousei Hospital - Department of Pulmonary Medicine, Kurashiki Central Hospital - Department of Respiratory Medicine, Nagasaki University, Kindai University, National Hospital Organization Kyushu Cancer Center, Niigata Cancer Center Hospital, National Cancer Center Hospital East, Saitama Cancer Center, Tokushima University, National Hospital Organization Hokkaido Medical Center, Kyushu University - Kyushu University Hospital, Kindai University, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology, National Cancer Center Hospital and Kyushu University - Kyushu University Hospital

Downloads 33 (1,277,121)

Abstract:

9.

Multicenter real-world data on first-line chemoimmunotherapy in patients with advanced non-small cell lung cancer and performance status 2: WJOG18424L

Number of pages: 45 Posted: 01 Oct 2025

affiliation not provided to SSRN, Juntendo University, Shizuoka Cancer Center, Juntendo University, Wakayama Medical University, Kindai University, Sendai Kousei Hospital, Kurashiki Central Hospital - Department of Respiratory Medicine, Kanagawa Cancer Center, affiliation not provided to SSRN, Kindai University, Niigata Cancer Center Hospital, Osaka International Cancer Institute, Kobe University, Kyushu University - Kyushu University Hospital, Kobe City Medical Center General Hospital, Kanagawa Cardiovascular and Respiratory Center, Kumamoto University - Kumamoto University Hospital, Hiroshima University - Hiroshima University Hospital, Nagasaki University, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology, Kyushu University - Kyushu University Hospital and Juntendo University - Department of Respiratory Medicine

Downloads 29 (1,332,057)

Abstract:

10.

Treatment-independent prognostic stratification using a nationwide registry of pleural mesothelioma in Japan

Number of pages: 36 Posted: 14 Mar 2026

The University of Osaka - Graduate School of Medicine, Hyogo Medical University - Department of Thoracic Surgery, Chiba University Graduate School of Medicine - Department of General Thoracic Surgery, Okayama Rosai Hospital, affiliation not provided to SSRN, Yokohama Sakae Kyosai Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Juntendo University - Department of Respiratory Medicine, Kyoto Prefectural University of Medicine, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology, Nippon Medical School - Department of Pulmonary Medicine and Oncology, Okayama University - Okayama University Hospital, Dokkyo Medical University, affiliation not provided to SSRN, University of Tsukuba - Department of Thoracic Surgery, affiliation not provided to SSRN, National Cancer Center Hospital, National Cancer Center Hospital - Department of Thoracic Surgery and Osaka University

Downloads 28 (1,345,526)

Abstract:

11.

Biological Impact of Chemotherapy During Treatment with Egfr Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer Positive for Egfr Activating Mutations

Number of pages: 22 Posted: 11 Jul 2025

Eiji Iwama, Kazuko Sakai, Taishi Harada, Shintaro Kanda, Shunichi Sugawara, Toshihide Yokoyama, Hirokazu Taniguchi, Kaoru Tanaka, Ryo Toyozawa, Kenichi Koyama, Yoshitaka Zenke, Gen Kida, Yasuhiko Nishioka, Hiroshi Yokouchi, Masayuki Hirose, Kazuto Nishio, Yuichiro Ohe, Nobuyuki Yamamoto and Isamu Okamoto

Kyushu University - Kyushu University Hospital, Kindai University - Kindai University Hospital, affiliation not provided to SSRN, Shinshu University - Department of Hematology and Medical Oncology, Sendai Kousei Hospital - Department of Pulmonary Medicine, Kurashiki Central Hospital - Department of Respiratory Medicine, Nagasaki University, Kindai University, National Hospital Organization Kyushu Cancer Center, Niigata Cancer Center Hospital, National Cancer Center Hospital East, Saitama Cancer Center, Tokushima University, National Hospital Organization Hokkaido Medical Center, Kyushu University - Kyushu University Hospital, Kindai University, National Cancer Center Hospital, Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology and Kyushu University - Kyushu University Hospital

Downloads 22 (1,424,331)

Nobuyuki Yamamoto

Wakayama Medical University - Department of Pulmonary Medicine and Medical Oncology

11

527

1

Scholarly Papers (11)

Radiotherapy-Free Pembrolizumab Combined with Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer with Pd-L1 TPS ≥50%: A Phase II Study (Evolution Trial: WJOG11819L)

Abstract:

Phase III Study of Cisplatin Plus Pemetrexed versus Cisplatin Plus Vinorelbine for Completely Resected Stage II-IIIA Non-Squamous Non-Small-Cell Lung Cancer: The JIPANG Study

Abstract:

Efficacy and Safety of Carboplatin With Nab-Paclitaxel Versus Docetaxel in Elderly Patients with Squamous-Cell Lung Cancer (CAPITAL): A Randomized, Multicenter, Open-Label, Phase III Trial

Abstract:

Efficacy of pembrolizumab plus pemetrexed in older patients with non-squamous NSCLC according to PD-L1 expression status: Results from the CJLSG1901 study

Abstract:

Durvalumab with Etoposide and Carboplatin for Patients with Extensive-Stage Small Cell Lung Cancer and Interstitial Lung Disease: A Multicenter, Open-Label Prospective Trial

Abstract:

A Phase II Study (WJOG12819L) to Assess the Efficacy of Osimertinib in Patients with EGFR Mutation-Positive NSCLC in Whom Systemic Disease (T790M-Negative) Progressed after Treatment with First- Or Second-Generation EGFR TKIS and Platinum-Based Chemotherapy

Abstract:

Longitudinal Analysis Reveals the Impact of Adjuvant Cytotoxic Chemotherapy in Egfr-Mutated Lung Cancer: A Combined Analysis of Phase Iii Studies

Abstract:

Biological Impact of Chemotherapy During Treatment with Egfr Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer Positive for Egfr Activating Mutations

Abstract:

Multicenter real-world data on first-line chemoimmunotherapy in patients with advanced non-small cell lung cancer and performance status 2: WJOG18424L

Abstract:

Treatment-independent prognostic stratification using a nationwide registry of pleural mesothelioma in Japan

Abstract:

Biological Impact of Chemotherapy During Treatment with Egfr Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer Positive for Egfr Activating Mutations

Abstract: