International University of Health and Welfare Hospital (IUHW) - Department of Internal Medicine, Keio University School of Medicine - Department of Physiology, Tokai University, Kitasato University - Division of Internal Medicine, Kitasato University, Keio University, International University of Health and Welfare Hospital (IUHW), International University of Health and Welfare Hospital (IUHW), International University of Health and Welfare Hospital (IUHW), International University of Health and Welfare Hospital (IUHW), International University of Health and Welfare Hospital (IUHW), Kitasato University, International University of Health and Welfare Hospital (IUHW), Keio University and Tokai University