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Genevieve Stein-O'Brien

Johns Hopkins University - Department of Neuroscience

Baltimore, MD 21218

United States

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Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development

Number of pages: 84 Posted: 02 Dec 2019
Yufeng Lu, Fion Shiau, Wenyang Yi, Suying Lu, Qian Wu, Joel Pearson, Alyssa Kallman, Suijuan Zhong, Thanh Hoang, Thanh Hoang, Zhentao Zuo, Fangqi Zhao, Mei Zhang, Nicole Tsai, Yan Zhuo, Sheng He, Jun Zhang, Genevieve Stein-O'Brien, Thomas D. Sherman, Xin Duan, Elana Fertig, Loyal Goff, Donald Zack, James Handa, Tian Xue, Rod Bremner, Seth Blackshaw, Xiaoqun Wang and Brian S. Clark
Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science, Washington University in St. Louis - Department of Ophthalmology and Visual Sciences, University of Science and Technology of China (USTC) - Hefei National Laboratory for Physical Sciences at the Microscale, Sinai Health Systems - Lunenfeld-Tanenbaum Research Institute, Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science, Sinai Health Systems - Lunenfeld-Tanenbaum Research Institute, Johns Hopkins University - Department of Ophthalmology, Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science, Johns Hopkins University - The Solomon H. Snyder Department of NeuroscienceJohns Hopkins University - Department of Neuroscience, Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science, Capital Medical University - Obstetrics and Gynecology Medical Center, University of Science and Technology of China (USTC) - Hefei National Laboratory for Physical Sciences at the Microscale, University of California, San Francisco (UCSF) - Department of Ophthalmology, Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science, Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science, Capital Medical University - Beijing Anzhen Hospital, Department of Obstetrics and Gynecology, Johns Hopkins University - Department of Neuroscience, Johns Hopkins University - Department of Oncology, University of California, San Francisco (UCSF) - Department of Ophthalmology, Johns Hopkins University - Department of Oncology, Johns Hopkins University - Department of Neuroscience, Johns Hopkins University - Department of Ophthalmology, Johns Hopkins University - Department of Ophthalmology, University of Science and Technology of China (USTC) - Hefei National Laboratory for Physical Sciences at the Microscale, Sinai Health Systems - Lunenfeld-Tanenbaum Research Institute, Johns Hopkins University - School of Medicine, Chinese Academy of Sciences (CAS) - State Key Laboratory of Brain and Cognitive Science and Washington University in St. Louis - Department of Ophthalmology and Visual Sciences
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Abstract:

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retina, neurogenesis, cell fate, patterning, fovea, transcription factors, single cell RNA-Seq, neurogenic bHLH factor, gene regulatory networks, organoid.