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Tim H. Brümmendorf

RWTH Aachen University - Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation

Germany

  • RWTH Aachen University - Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation

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Dissecting the Functional Reprogramming of the Microenvironment in Bone Marrow Fibrosis at the Single Cell Level

Number of pages: 42 Posted: 03 Dec 2019
Nils B. Leimkühler, Li Ronghui, Hélène F.E. Gleitz, Inge A. M. Snoeren, Stijn N.R. Fuchs, Christoph Kuppe, Ursula S. A. Stalmann, Guntram Buesche, Hans Kreipe, Ines Gütgemann, Philippe Krebs, Yara Banz, Peter Boor, Evelyn Wing-Ying Tai, Tim H. Brümmendorf, Steffen Koschmieder, Martina Crysandt, Eric Bindels, Rafael Kramann, Ivan G. Costa and Rebekka K. Schneider
Erasmus Medical Center - Department of Hematology, RWTH Aachen University - Institute for Computational Genomics, Erasmus Medical Center - Department of Hematology, Erasmus Medical Center - Department of Hematology, Erasmus Medical Center - Department of Hematology, RWTH Aachen University - Division of Nephrology and Clinical Immunology, Erasmus Medical Center - Department of Hematology, Hannover Medical School - Institute of Pathology, Hannover Medical School - Institute of Pathology, University of Bonn - Institute of Pathology, University of Bern - Institute of Pathology, University of Bern - Institute of Pathology, RWTH Aachen University - Division of Nephrology and Clinical Immunology, RWTH Aachen University - Institute of Pathology, RWTH Aachen University - Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, RWTH Aachen University - Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, RWTH Aachen University - Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Erasmus Medical Center - Department of Hematology, RWTH Aachen University - Division of Nephrology and Clinical Immunology, RWTH Aachen University - Interdisciplinary Centre for Clinical Research (IZKF) and Erasmus Medical Center - Department of Hematology
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Abstract:

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Hematopoietic stem cells, Mesenchymal Stromal Cells, bone marrow, microenvironment, fibrosis, single cell RNA sequencing, myeloproliferative neoplasm, biomarker, cell fate, disease modelling