Case Western Reserve University - Center for Computational Imaging and Personalized Diagnostics, Cleveland Clinic - Department of Radiation Oncology, Case Western Reserve University - Center for Computational Imaging and Personalized Diagnostics, Case Western Reserve University - Center for Computational Imaging and Personalized Diagnostics, Cleveland Clinic - Imaging Institute, Cleveland Clinic - Imaging Institute, Case Western Reserve University - Department of Population & Quantitative Health Sciences, Case Western Reserve University - Center for Computational Imaging and Personalized Diagnostics, Cleveland Clinic - Department of Radiation Oncology, Vanderbilt University - Department of Pathology, Microbiology and Immunology and Emory University - Wallace H Coulter Department of Biomedical Engineering