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Hannah R. Foster

University of Wisconsin-Madison - Department of Medicine

716 Langdon Street

Madison, WI 53706-1481

United States

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1.

Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway

Number of pages: 38 Posted: 22 Jan 2020
Sophie L. Lewandowski, Rebecca L. Cardone, Hannah R. Foster, Thuong Ho, Evgeniy Potapenko, Chetan Poudel, Halena R. VanDeusen, Tiago Alves, Xiaojian Zhao, Megan E. Capozzi, Ishrat Jahan, Craig S. Nunemaker, Jonathan E. Campbell, Craig J. Thomas, Richard G. Kibbey and Matthew J. Merrins
University of Wisconsin-Madison - Department of Medicine, Yale University - Department of Internal Medicine, University of Wisconsin-Madison - Department of Medicine, University of Wisconsin-Madison - Department of Medicine, University of Wisconsin-Madison - Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison - Department of Medicine, University of Wisconsin-Madison - Department of Medicine, Yale University - Department of Internal Medicine, Yale University - Department of Internal Medicine, Duke University - Duke Molecular Physiology Institute, Ohio University - Department of Biomedical Sciences, Ohio University - Department of Biomedical Sciences, Duke University - Duke Molecular Physiology Institute, National Institutes of Health - Division of Preclinical Innovation, Yale University - Department of Internal Medicine and University of Wisconsin-Madison - Division of Endocrinology, Diabetes, and Metabolism
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Abstract:

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Pyruvate kinase, KATP channel, Insulin Secretion, β-cell metabolism, Oxidative phosphorylation, phosphoenolpyruvate cycle, anaplerosis, metabolic oscillations, biosensor imaging, metabolic flux