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Tobias B. Dansen

Utrecht University - Center for Molecular Medicine

Netherlands

  • Utrecht University - Center for Molecular Medicine

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A FOXO-Dependent Replication Checkpoint Restricts Proliferation of Damaged Cells

Number of pages: 38 Posted: 19 Feb 2020
Marten Hornsveld, Femke M. Feringa, Lenno Krenning, Jeroen van den Berg, Lydia M.M. Smits, Nguyen BT Nguyen, Maria J. Rodriguez Colman, Tobias B. Dansen, Rene H. Medema and Boudewijn M.T. Burgering
Leiden University - Department of Cell and Chemical Biology, Netherlands Cancer Institute - Division of Cell Biology, Netherlands Cancer Institute - Division of Cell Biology, Netherlands Cancer Institute - Division of Cell Biology, Utrecht University - Center for Molecular Medicine, Utrecht University - Center for Molecular Medicine, University Medical Center Utrecht - Oncode Institute and Department of Molecular Cancer Research, Utrecht University - Center for Molecular Medicine, Netherlands Cancer Institute - Division of Cell Biology and University Medical Center Utrecht - Oncode Institute and Department of Molecular Cancer Research
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Abstract:

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DNA replication stress, cell cycle exit, FOXO transcription factors, cell cycle checkpoint