Shanghai Jiao Tong University (SJTU) - Department of Endocrinology and Metabolism, Shanghai Jiao Tong University (SJTU) - Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Jiao Tong University (SJTU) - Shanghai Clinical Center for Endocrine and Metabolic Diseases, Chinese Academy of Sciences (CAS) - Shanghai Institute of Nutrition and Health, Shanghai Jiao Tong University (SJTU) - Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Jiao Tong University (SJTU) - Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Jiao Tong University (SJTU) - Shanghai National Clinical Research Center for Endocrine and Metabolic Diseases, Changchun University and Shanghai Jiao Tong University (SJTU) - Department of Endocrine and Metabolic Diseases