University of Vienna - Department of Biochemistry and Cell Biology, The Berlin Institute for Medical Systems Biology, University of Vienna - Department of Biochemistry and Cell Biology, University of Vienna - Department of Structural and Computational Biology, Masaryk University - Central European Institute of Technology, Vienna Biocenter - Research Institute of Molecular Pathology (IMP), University of Vienna - Department of Structural and Computational Biology, University of Vienna - Department of Biochemistry and Cell Biology, University of Vienna - Department of Biochemistry and Cell Biology, University of Vienna - Research Institute of Molecular Pathology, University of Vienna - Research Institute of Molecular Pathology, University of Vienna - Research Institute of Molecular Pathology, University of Vienna - Department of Microbiology, Immunobiology and Genetics, University of Vienna - Research Institute of Molecular Pathology, University of Vienna - Research Institute of Molecular Pathology, The Berlin Institute for Medical Systems Biology, Masaryk University - Central European Institute of Technology, Institute of Science and Technology Austria (ISTA), University of Vienna - Department of Structural and Computational Biology and University of Vienna - Department of Biochemistry and Cell Biology