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Elin M. Svensson

Radboud University Nijmegen - Department of Pharmacy

Department of Pharmacy,

Netherlands

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Scholarly Papers (1)

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Increased Bactericidal Activity But Dose-Limiting Tolerability at 50 mg/kg Rifampicin

Number of pages: 41 Posted: 31 Mar 2020
Lindsey te Brake, Veronique de Jager, Kim Narunsky, Naadira Vanker, Elin M. Svensson, Patrick PJ Phillips, Stephen H Gillespie, Norbert Heinrich, Michael Hoelscher, Rodney Dawson, Andreas H. Diacon, Rob E. Aarnoutse, Martin J. Boeree and PanACEA Consortium Group
Radboud University Nijmegen - Department of Lung Disease, TASK Applied Science, University of Cape Town (UCT) - University of Cape Town Lung Institute, TASK Applied Science, Radboud University Nijmegen - Department of Pharmacy, University of California, San Francisco (UCSF) - UCSF Center for Tuberculosis, St. Andrews University, Ludwig Maximilian University of Munich (LMU) - Division of Infectious Diseases and Tropical Medicine, Ludwig Maximilian University of Munich (LMU) - CIHLMU Center for International Health, University of Cape Town Lung Institute, TASK Applied Science, Radboud University Nijmegen - Department of Pharmacy, Radboud University Nijmegen - Department of Lung Disease and Independent
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Abstract:

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maximum tolerable dose; high-dose rifampicin; pharmacokinetics; early bactericidal activity; dose optimization; exposure-response