Southeast University - Department of Critical Care Medicine, University of Liverpool - Institute of Infection and Global Health, Soochow University - Department of Intensive Care Medicine, University of Liverpool - Institute of Infection and Global Health, Huazhong University of Science and Technology - Department of Emergency Medicine, University of Liverpool - Institute of Infection and Global HealthSoutheast University - Department of Critical Care Medicine, Capital Medical University - Department of Respiratory and Critical Care Medicine, Capital Medical University - Department of Respiratory and Critical Care Medicine, University of Liverpool - Department of Biostatistics, Yangzhou University - Department of Critical Care Medicine, Capital Medical University - Department of Respiratory and Critical Care Medicine, Capital Medical University - Department of Respiratory and Critical Care Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC), Southeast University - Department of Critical Care Medicine and University of Liverpool - Institute of Infection and Global Health