Sun Yat-sen University (SYSU) - Department of Hematologic Oncology, Guangzhou Medical University - Department of Hematology, Sun Yat-sen University (SYSU) - Department of Hematologic Oncology, University of Texas at Houston - UT Health Graduate School of Biomedical Sciences, State Key Laboratory of Oncology in South China and Shanghai Jiao Tong University (SJTU) - National Research Center for Translational Medicine