University of Montreal - Department of Pharmacology and Physiology, University of Montreal - Department of Pharmacology and Physiology, Université Laval - Department of Molecular Medicine, University of Montreal - Department of Pharmacology and Physiology, Children's Hospital Boston - F.M. Kirby Neurobiology Center, Children's Hospital Boston - F.M. Kirby Neurobiology Center, Children's Hospital Boston - F.M. Kirby Neurobiology Center, Sanford Research, Cygnal Therapeutics, Cygnal Therapeutics, University of Montreal - Department of Pharmacology and Physiology, University of Montreal - Department of Pharmacology and Physiology, Children's Hospital Boston - F.M. Kirby Neurobiology Center, Massachusetts General Hospital, Universidade Federal de Santa Catarina (UFSC), University of Montreal - Department of Pharmacology and Physiology, Université Laval - Department of Molecular Medicine, McGill University - Gerald Bronfman Department of Oncology, Cygnal Therapeutics, University of Pennsylvania, Université Laval - Department of Molecular Medicine, Children's Hospital Boston - F.M. Kirby Neurobiology Center, Sanford Research and University of Montreal - Department of Pharmacology and Physiology