Peking University - Department of Gastroenterology and Hepatology, Shanghai Jiao Tong University (SJTU) - Department of Critical Care Medicine, Peking University - Department of Gastroenterology and Hepatology, Peking University - Department of Gastroenterology and Hepatology, Peking University - Department of Gastroenterology and Hepatology, University of Michigan at Ann Arbor, Peking University, Peking University - Department of Gastroenterology and Hepatology, Peking University - Department of Gastroenterology and Hepatology, Chinese Academy of Sciences (CAS) - CAS Key Laboratory of Pathogenic Microbiology and Immunology, Chinese Academy of Sciences (CAS) - CAS Key Laboratory of Pathogenic Microbiology and Immunology, University of Michigan at Ann Arbor and Peking University - Department of Gastroenterology and Hepatology