Brunel University London - Institute of Environment, University of São Paulo (USP), IRCCS Istituto Giannina Gaslini, IRCCS Istituto Giannina Gaslini, IRCCS Istituto Giannina Gaslini, Brunel University London - Institute of Environment, Brunel University London - Institute of Environment, Institute of Cancer Research (ICR), Institute of Cancer Research (ICR), Fondazione Santa Lucia, University of Southern Denmark - Department of Biochemistry and Molecular Biology, University of São Paulo (USP) and Brunel University London