University of Pisa - Islet Cell Laboratory, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, University of Pisa - Department of Clinical and Experimental Medicine, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, University of Lille, Imperial College London, University of Pisa - Department of Clinical and Experimental Medicine, University of Pisa - Department of Clinical and Experimental Medicine, 'Gabriele d'Annunzio' University of Chieti-Pescara, University of Lausanne - Swiss Institute of Bioinformatics (SIB), Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, University of Pisa - Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa - Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa - Department of Translational Research on New Technologies in Medicine and Surgery, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, University of Pisa - Department of Clinical and Experimental Medicine, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, University of Pisa - Department of Translational Research on New Technologies in Medicine and Surgery, Sanofi-Aventis Deutschland GmbH, TU Dresden - Paul Langerhans Institute of the Helmholtz Center Munich, Sanofi-Aventis Deutschland GmbH, Janssen Research & Development, LLC, Janssen Research & Development, LLC, Janssen Research & Development, LLC, Janssen Research & Development, LLC, University of Lausanne - Center for Integrative Genomics, University of Lille, University of Lille, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research, Université Libre de Bruxelles (ULB) - ULB Center for Diabetes Research and University of Pisa - Islet Cell Laboratory