Shirin Kalimuddin

National University of Singapore (NUS) - Department of Infectious Diseases

Singapore

Duke NUS Medical School - Emerging Infectious Disease Program

Singapore

SCHOLARLY PAPERS

9

DOWNLOADS

1,006

TOTAL CITATIONS

18

Scholarly Papers (9)

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1.

Immunological and Viral Correlates of COVID-19 Disease Severity: A Prospective Cohort Study of the First 100 Patients in Singapore

Number of pages: 34 Posted: 20 May 2020
Barnaby E. Young, Sean Wei Xiang Ong, Lisa FP Ng, Danielle E. Anderson, Wan Ni Chia, Po Ying Chia, Li Wei Ang, Tze-Minn Mak, Shirin Kalimuddin, Louis Yi Ann Chai, Surinder Pada, Seow Yen Tan, Louisa Sun, Purmina Parthasarathy, Siew-Wai Fong, Yi-Hao Chan, Chee Wah Tan, Bernett Lee, Olaf Rötzschke, Ying Ding, Paul Tambyah, Jenny GH Low, Lin Cui, Timothy Barkham, Raymond Tzer Pin Lin, Yee-Sin Leo, Laurent Renia, Lin-Fa Wang, David Chien Lye and Singapore 2019 Novel Coronavirus Outbreak Research Team
National Centre for Infectious Diseases, Singapore, National Centre for Infectious Diseases, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Duke NUS Medical School, Duke-NUS Medical School - Programme in Emerging Infectious Diseases, National Centre for Infectious Diseases, Singapore, Ministry of Health, Singapore, National Centre for Infectious Diseases, Singapore, National University of Singapore (NUS) - Department of Infectious Diseases, National University Health System (NUHS), Ng Teng Fong General Hospital - Division of Infectious Diseases, Changi General Hospital, Alexandra Hospital, Khoo Teck Puat Hospital, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Duke NUS Medical School, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National Centre for Infectious Diseases, National University of Singapore (NUS), National University of Singapore (NUS) - Singapore General Hospital, National Centre for Infectious Diseases, Singapore, Tan Tock Seng Hospital, National Centre for Infectious Diseases, National University of Singapore (NUS) - Department of Microbiology and Immunology, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Duke NUS Medical School, National Centre for Infectious Diseases and Independent
Downloads 605 (95,756)
Citation 5

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Coronavirus Disease 2019; COVID-19; severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; severe; critical illness; IL-6; serology; viral culture

2.

Linear B-Cell Epitopes in the Spike and Nucleocapsid Proteins as Markers of SARS-CoV-2 Exposure and Disease Severity

Number of pages: 38 Posted: 12 Jun 2020
Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Bernett Lee, Siew-Wai Fong, Barnaby E. Young, Rhonda Sin-Ling Chee, Nicholas Kim-Wah Yeo, Anthony Torres-Ruesta, Guillaume Carissimo, Chek Meng Poh, Zi Wei Chang, Matthew Zirui Tay, Yi-Hao Chan, Mark I-Cheng Chen, Paul A. Tambyah, Shirin Kalimuddin, Surinder Pada, Seow Yen Tan, Louisa Jin Sun, Yee-Sin Leo, David Chien Lye, Laurent Renia and Lisa FP Ng
Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National Centre for Infectious Diseases, Singapore, Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National Centre for Infectious Diseases, National Centre for Infectious Diseases, National University of Singapore (NUS) - Department of Infectious Diseases, Ng Teng Fong General Hospital - Division of Infectious Diseases, Changi General Hospital, Alexandra Hospital, National University of Singapore (NUS) - Department of Microbiology and Immunology, National Centre for Infectious Diseases, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN) and Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN)
Downloads 143 (432,700)
Citation 6

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epitopes; SARS-CoV-2; COVID-19; patients; biomarkers

3.

Gut Ruminococcaceae Levels Correlate with Risk of Antibiotic-Associated Diarrhea

Number of pages: 28 Posted: 19 Aug 2021
Xiaoqiong Gu, Jean XY Sim, Wei Lin Lee, Yvonne FZ Chan, Ega Danu Chang, Yii Ean Teh, An-Ni Zhang, Federica Armas, Franciscus Chandra, Chen Hongjie, Shijie Zhao, Zhanyi Lee, Janelle R. Thompson, Eng Eong Ooi, Jenny G. Low, Eric J. Alm and Shirin Kalimuddin
Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, National University of Singapore (NUS) - Department of Infection Prevention and Epidemiology, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, National University of Singapore (NUS) - Department of Infectious Diseases, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, National University of Singapore (NUS) - Department of Infectious Diseases, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Nanyang Technological University (NTU) - Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Duke-NUS Medical School - Program in Emerging Infectious Diseases, National University of Singapore (NUS) - Department of Infectious Diseases, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group and National University of Singapore (NUS) - Department of Infectious Diseases
Downloads 59 (769,111)

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4.

Association of SARS-CoV-2 Clades with Clinical, Inflammatory and Virologic Outcomes: An Observational Study

Number of pages: 33 Posted: 05 Jan 2021
Barnaby E. Young, Wycliffe E. Wei, Siew-Wai Fong, Tze-Minn Mak, Danielle E. Anderson, Yi-Hao Chan, Rachael Pung, Cheryl SY Heng, Li Wei Ang, Kang Eng Zheng, Bernett Lee, Shirin Kalimuddin, Surinder Pada, Paul A. Tambyah, Purnima Parthasarathy, Seow-Yen Tan, Louisa Sun, Gavin JD Smith, Raymond Tzer Pin Lin, Yee-Sin Leo, Laurent Renia, Lin-Fa Wang, Lisa F.P. Ng, Sebastian Maurer-Stroh, David Chien Lye and Vernon J. Lee
National Centre for Infectious Diseases, Singapore, National Public Health and Epidemiology Unit, National Centre for Infectious Diseases, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National Centre for Infectious Diseases, Singapore, Duke NUS Medical School, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Government of the Republic of Singapore - Communicable Diseases Division, Ministry of Health, Singapore, National Centre for Infectious Diseases, Singapore, Duke NUS Medical School, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National University of Singapore (NUS) - Department of Infectious Diseases, Ng Teng Fong General Hospital - Division of Infectious Diseases, National University Health System, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Khoo Teck Puat Hospital, Changi General Hospital - Department of Infectious Diseases, Alexandra Hospital, Duke-NUS Medical School, National Centre for Infectious Diseases, National University of Singapore (NUS) - Department of Microbiology and Immunology, Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Duke NUS Medical School, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Bioinformatics Institute, Nanyang Technological University (NTU) - Lee Kong Chian School of Medicine and Ministry of Health, Singapore
Downloads 58 (775,655)

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5.

Early T Cell and Binding Antibody Responses are Associated with COVID-19 RNA Vaccine Efficacy Onset

Number of pages: 23 Posted: 02 Mar 2021
Shirin Kalimuddin, Christine YL Tham, Martin Qui, Ruklanthi de Alwis, Jean XY Sim, Joey ME Lim, Hwee-Cheng Tan, Ayesa Syenina, Summer L. Zhang, Nina Le Bert, Anthony T. Tan, Yan Shan Leong, Jia Xin Yee, Eugenia Z. Ong, Eng Eong Ooi, Antonio Bertoletti and Jenny G. Low
National University of Singapore (NUS) - Department of Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, National University of Singapore (NUS) - Centre for Outbreak Preparedness, National University of Singapore (NUS) - Department of Infection Prevention and Epidemiology, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Programme in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School - Programme in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases and National University of Singapore (NUS) - Department of Infectious Diseases
Downloads 47 (857,042)
Citation 5

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6.

Immune Landscape of 382-Nt Deleted SARS-CoV-2 Reveals Heightened Adaptive Response Indicating Prophylactic Potential Against COVID-19

Number of pages: 90 Posted: 21 Oct 2020
Siew-Wai Fong, Nicholas Kim-Wah Yeo, Yi-Hao Chan, Yun Shan Goh, Siti Naqiah Amrun, Nicholas Ang, Josephine Lum, Shihui Foo, Cheryl Yi-Pin Lee, Guillaume Carissimo, Rhonda Sin-Ling Chee, Anthony Torres-Ruesta, Matthew Zirui Tay, Zi Wei Chang, Chek Meng Poh, Barnaby E. Young, Paul A. Tambyah, Shirin Kalimuddin, Yee-Sin Leo, David Chien Lye, Bernett Lee, Subhra Biswas, Shanshan W. Howland, Laurent Renia and Lisa F.P. Ng
Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, National Centre for Infectious Diseases, Singapore, National Centre for Infectious Diseases, National University of Singapore (NUS) - Department of Infectious Diseases, National University of Singapore (NUS) - Department of Microbiology and Immunology, Nanyang Technological University (NTU) - Lee Kong Chian School of Medicine, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN) and Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN)
Downloads 34 (977,092)

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COVID-19, SARS-CoV-2, transcriptome, ORF8, deletion, RNA-seq

7.

Baseline Enrichment of T and NK Cell Genes Predispose to mRNA Vaccine-Associated Systemic Adverse Events that Can Be Alleviated by Altering the Route of Vaccination

Number of pages: 43 Posted: 14 Dec 2021
Ayesa Syenina, Esther S. Gan, Justin ZN Toh, Ruklanthi de Alwis, Lowell Z. Lin, Christine YL Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L.E. Wee, Dorothy H.L. Ng, Chan Rong, Jean XY Sim, Shirin Kalimuddin, Eugenia Z. Ong, Jenny G. Low and Eng Eong Ooi
Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Nanyang Polytechnic, National University of Singapore (NUS) - Centre for Outbreak Preparedness, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, National University of Singapore (NUS) - Singapore General Hospital, National University of Singapore (NUS) - Singapore General Hospital, National University of Singapore (NUS) - Department of Infectious Diseases, National University of Singapore (NUS) - Singapore General Hospital, National University of Singapore (NUS) - Singapore General Hospital, National University of Singapore (NUS) - Programme in Emerging Infectious Diseases, National University of Singapore (NUS) - Department of Infection Prevention and Epidemiology, National University of Singapore (NUS) - Department of Infectious Diseases, Duke-NUS Medical School - Program in Emerging Infectious Diseases, National University of Singapore (NUS) - Department of Infectious Diseases and Duke-NUS Graduate Medical School - Programme in Emerging Infectious Diseases
Downloads 25 (1,078,324)

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COVID-19 vaccine, mRNA vaccine, systemic adverse events, fatigue, vaccination route Introduction

8.

Sensitive Detection of Total Anti-Spike Antibodies and Isotype Switching in Asymptomatic and Symptomatic COVID-19 Patients

Number of pages: 44 Posted: 23 Oct 2020
Yun Shan Goh, Jean-Marc Chavatte, Alicia Lim Jieling, Bernett Lee, Siti Naqiah Amrun, Cheryl Yi-Pin Lee, Rhonda Sin-Ling Chee, Bei Wang, Chia Yin Lee, Eve Ngoh, Cheng-I Wang, Barnaby E. Young, Paul A. Tambyah, Shirin Kalimuddin, Surinder Pada, Seow-Yen Tan, Louisa Sun, Mark I-Cheng Chen, Yee-Sin Leo, David Chien Lye, Lisa F.P. Ng, Raymond Tzer Pin Lin and Laurent Renia
Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, National Centre for Infectious Diseases, National Centre for Infectious Diseases, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National Centre for Infectious Diseases, Singapore, National Centre for Infectious Diseases, National University of Singapore (NUS) - Department of Infectious Diseases, Ng Teng Fong General Hospital - Division of Infectious Diseases, Changi General Hospital - Department of Infectious Diseases, Alexandra Hospital, National Centre for Infectious Diseases, National University of Singapore (NUS) - Department of Microbiology and Immunology, Nanyang Technological University (NTU) - Lee Kong Chian School of Medicine, Agency for Science, Technology and Research (A*STAR) - Singapore Immunology Network (SIgN), National Centre for Infectious Diseases and Agency for Science, Technology and Research (A*STAR) - Infectious Diseases Horizontal Technology Centre
Downloads 21 (1,128,248)
Citation 2

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SARS-CoV-2, COVID-19, serological, S protein, antibodies, IgG subclasses, symptomatic, asymptomatic

9.

Gut Ruminococcaceae Levels Correlate with Risk of Antibiotic-Associated Diarrhea

Number of pages: 44 Posted: 14 Oct 2021
Xiaoqiong Gu, Jean XY Sim, Wei Lin Lee, Liang Cui, Yvonne FZ Chan, Ega Danu Chang, Yii Ean Teh, An-Ni Zhang, Federica Armas, Franciscus Chandra, Chen Hongjie, Shijie Zhao, Zhanyi Lee, Janelle R. Thompson, Eng Eong Ooi, Jenny G. Low, Eric J. Alm and Shirin Kalimuddin
Singapore-MIT Alliance for Research and Technology, National University of Singapore (NUS) - Department of Infection Prevention and Epidemiology, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, National University of Singapore (NUS) - Department of Infectious Diseases, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, National University of Singapore (NUS) - Department of Infectious Diseases, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Singapore-MIT Alliance for Research and Technology, Nanyang Technological University (NTU) - Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Duke-NUS Graduate Medical School - Programme in Emerging Infectious Diseases, National University of Singapore (NUS) - Department of Infectious Diseases, Singapore-MIT Alliance for Research and Technology - Antimicrobial Resistance Interdisciplinary Research Group and National University of Singapore (NUS) - Department of Infectious Diseases
Downloads 14 (1,214,986)

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Antibiotic-associated diarrhea (AAD), amoxicillin-clavulanate, Gut microbiome, Ruminococcaceae, F. prausnitzii