David I. Stuart

Weizmann Institute of Science - Department of Biomolecular Sciences

Israel

University of Oxford - Division of Structural Biology

United Kingdom

SCHOLARLY PAPERS

4

DOWNLOADS

187

TOTAL CITATIONS

11

Scholarly Papers (4)

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Number of pages: 58 Posted: 01 Jun 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Public Health England - National Infection Service, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, Public Health England - National Infection Service, Public Health England - National Infection Service, Public Health England - National Infection Service, Diamond Light Source, Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, Public Health England - National Infection Service, University of Oxford - MRC Human Immunology Unit, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and Weizmann Institute of Science - Department of Biomolecular Sciences
Downloads 33 (1,014,116)
Citation 3

Abstract:

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SARS-CoV-2, Spike, X-ray crystallography, Cryo-EM, Neutralisation, Monoclonal antibody, neutralising monoclonal antibody, COVID-19

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Number of pages: 53 Posted: 12 May 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Public Health England - National Infection Service, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - MRC Human Immunology Unit, University of Oxford - MRC Human Immunology Unit, Public Health England - National Infection Service, Public Health England - National Infection Service, Diamond Light Source, Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Trust Centre for Human Genetics, Public Health England - National Infection Service, University of Oxford - MRC Human Immunology Unit, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and Weizmann Institute of Science - Department of Biomolecular Sciences
Downloads 32 (1,025,329)

Abstract:

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Covid-19, SARS-CoV-2, Antibody Structure, Spike, Receptor Binding Domain, Neutralisation, Therapeutic Antibody, Crystallography, Cryo-EM, virus structure

2.

­­­The Antigenic Anatomy of SARS-CoV-2 Receptor Binding Domain

Number of pages: 87 Posted: 23 Dec 2020
University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, Diamond Light Source Ltd - Harwell Science & Innovation Campus, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Pathology and Immunology, Washington University School of Medicine - Department of Medicine, Washington University in St. Louis - Department of Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Department of Zoology, University of Oxford - MRC Human Immunology Unit, University of Oxford - Sir William Dunn School of Pathology, University of Oxford - Sir William Dunn School of Pathology, Public Health England - National Infection Service, Public Health England - National Infection Service, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation TrustUniversity of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford - Oxford Vaccine Group, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Worthing Hospital, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Kent - Viral Pseudotype Unit, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - MRC Human Immunology Unit, Chang Gung University - Research Center for Emerging Viral Infections, University of Oxford - Division of Structural Biology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Washington University School of Medicine - Department of Medicine, University of Oxford - Division of Structural Biology, Weizmann Institute of Science - Department of Biomolecular Sciences and University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI)
Downloads 53 (810,528)
Citation 7

Abstract:

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SARS-CoV-2, antibody, germline, V-gene, receptor-binding-domain, spike, neutralisation, protection, glycosylation, valency

3.

Receptor Binding and Escape From Beta Antibody Responses Drive Omicron-B.1.1.529 Evolution

Number of pages: 50 Posted: 03 Dec 2021
Weizmann Institute of Science - Department of Biomolecular Sciences, University of Oxford - Wellcome Centre for Human Genetics, Diamond Light Source Ltd - Harwell Science & Innovation Campus, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Weizmann Institute of Science - Department of Biomolecular Sciences, Weizmann Institute of Science - Department of Biomolecular Sciences, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Kent - Viral Pseudotype Unit, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Weizmann Institute of Science - Department of Biomolecular Sciences and Weizmann Institute of Science - Department of Biomolecular Sciences
Downloads 52 (817,921)

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SARS-CoV-2, Omicron, Variants, Vaccines, Immune Evasion, Receptor Interaction, Spike, RBD

4.

The SARS-CoV-2 Spike Harbours a Lipid Binding Pocket Which Modulates Stability of the Prefusion Trimer

Number of pages: 37 Posted: 10 Aug 2020
University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, Diamond Light Source, Harwell Science and Innovation Campus, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology and Weizmann Institute of Science - Department of Biomolecular Sciences
Downloads 17 (1,178,180)
Citation 1

Abstract:

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