James Brett Case

Washington University in St. Louis - Department of Medicine

St. Louis, MO 63110

United States

SCHOLARLY PAPERS

5

DOWNLOADS

117

SSRN CITATIONS

3

CROSSREF CITATIONS

0

Scholarly Papers (5)

1.

­­­The Antigenic Anatomy of SARS-CoV-2 Receptor Binding Domain

Number of pages: 87 Posted: 23 Dec 2020
University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, Diamond Light Source Ltd - Harwell Science & Innovation Campus, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, University of Oxford - Division of Structural Biology, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Trust Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Wellcome Centre for Human Genetics, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Pathology and Immunology, Washington University School of Medicine - Department of Medicine, Washington University in St. Louis - Department of Medicine, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Peter Medawar Building for Pathogen Research, University of Oxford - Department of Zoology, University of Oxford - MRC Human Immunology Unit, University of Oxford - Sir William Dunn School of Pathology, University of Oxford - Sir William Dunn School of Pathology, Public Health England - National Infection Service, Public Health England - National Infection Service, University of Oxford - Wellcome Centre for Human Genetics, Oxford University Hospitals NHS Foundation TrustUniversity of Oxford - Nuffield Department of Clinical Neurosciences, University of Oxford - Oxford Vaccine Group, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), Worthing Hospital, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Oxford - Wellcome Centre for Human Genetics, University of Oxford - Peter Medawar Building for Pathogen Research, University of Kent - Viral Pseudotype Unit, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, Diamond Light Source - Harwell Science and Innovation Campus, University of Oxford - MRC Human Immunology Unit, Chang Gung University - Research Center for Emerging Viral Infections, University of Oxford - Division of Structural Biology, University of Oxford - Wellcome Centre for Human Genetics, Washington University School of Medicine - Department of Medicine, University of Oxford - Division of Structural Biology, Weizmann Institute of Science - Department of Biomolecular Sciences and University of Oxford - Wellcome Centre for Human Genetics
Downloads 42 (556,723)
Citation 3

Abstract:

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SARS-CoV-2, antibody, germline, V-gene, receptor-binding-domain, spike, neutralisation, protection, glycosylation, valency

2.

SARS-CoV-2 Ferritin Nanoparticle Vaccines Elicit Broad SARS Coronavirus Immunogenicity

Number of pages: 150 Posted: 27 May 2021
Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research - Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research - Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research - Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research - Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, National Institutes of Health (NIH) - Center for Molecular Microscopy, Washington University School of Medicine - Department of Medicine, Walter Reed Army Institute of Research - Viral Diseases Branch, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Washington University in St. Louis - Department of Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Henry M. Jackson Foundation for the Advancement of Military Medicine, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, University of Maryland, School of Medicine, Institute of Human Virology, Division of Vaccine Research, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Henry M. Jackson Foundation for the Advancement of Military Medicine, Walter Reed Army Institute of Research - Viral Diseases Branch, Walter Reed Army Institute of Research - Viral Diseases Branch, Henry M. Jackson Foundation for the Advancement of Military Medicine, National Institutes of Health (NIH) - Center for Molecular Microscopy, National Institutes of Health (NIH) - Center for Molecular Microscopy, Trudeau Institute, Inc., Trudeau Institute, Inc., Trudeau Institute, Inc., Trudeau Institute, Inc., Trudeau Institute, Inc., Walter Reed Army Institute of Research - Viral Diseases Branch, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, AstraZeneca Pharmaceuticals - Antibody Discovery and Protein Engineering (ADPE), AstraZeneca Pharmaceuticals - Microbial Sciences, AstraZeneca Pharmaceuticals - Microbial Sciences, Trudeau Institute, Inc., Walter Reed Army Institute of Research, National Institutes of Health (NIH) - Center for Molecular Microscopy, Washington University School of Medicine - Department of Medicine, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research - U.S. Military HIV Research Program, Walter Reed Army Institute of Research and Walter Reed Army Institute of Research - Emerging Infectious Diseases Branch
Downloads 38 (577,091)

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SARS-CoV-2, ferritin nanoparticle, Spike, receptor binding domain, COVID-19, SARS-CoV-1, β-coronaviruses, variants of concern, B.1.1.7, B.1.351, P.1, ALFQ, neutralizing antibodies

3.

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

Number of pages: 39 Posted: 27 May 2020
Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Biochemistry and Molecular Biophysics, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Medicine, University of Toronto - The Donnelly Centre, University of Toronto - The Donnelly Centre, University of Toronto - The Donnelly Centre, Vir Biotechnology, Washington University in St. Louis - Department of Molecular Microbiology, Washington University in St. Louis - Department of Molecular Microbiology, Humabs Biomed, Mayo Clinic - Division of Clinical Microbiology, Washington University in St. Louis - Division of Immunobiology, Washington University in St. Louis - Department of Medicine and Washington University in St. Louis - Department of Molecular Microbiology
Downloads 20 (693,644)
Citation 2

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vesicular stomatitis virus, coronavirus spike, SARS-CoV-2, Neutralization Assay

4.

A Single Intranasal or Intramuscular Immunization with Chimpanzee Adenovirus Vectored SARS-CoV-2 Vaccine Protects Against Pneumonia in Hamsters

Number of pages: 41 Posted: 26 Jan 2021
Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Division of Immunobiology, Washington University in St. Louis - Department of Pathology and Immunology, Washington University in St. Louis - Department of Pathology and Immunology, Washington University in St. Louis - Department of Internal Medicine, Washington University in St. Louis - Department of Pathology and Immunology, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Division of Immunobiology, Washington University in St. Louis - Department of Internal Medicine, Washington University School of Medicine - Department of Medicine and Washington University in St. Louis - Department of Internal Medicine
Downloads 9 (788,227)

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5.

Rationally Designed Immunogens Enable Immune Focusing Following SARS-CoV-2 Spike Imprinting

Number of pages: 62 Posted: 10 Nov 2021
Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Washington University in St. Louis - Department of Medicine, Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Washington University School of Medicine - Department of Medicine, Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard and Ragon Institute of MGH, MIT and Harvard
Downloads 8 (797,908)

Abstract:

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immunogen design, glycan, immune focusing, SARS-CoV-2, Coronavirus