University of Pennsylvania - Section of Hospital Medicine, Departmentof Departmentof Biostatistics and Bioinformatics, Duke University, Division of Pediatric Infectious Diseases, Duke University, Division of Pediatric Infectious Diseases, Duke University, heRyan White Center for Pediatric Infectious Disease and Global Health, Indiana University School of Medicine, Divisionof General Pediatrics, Children’s Hospital of Philadelphia, Botswana–UPenn Partnership, Ministry of Health, Botswana, Department of Family Medicine and Public Health, University of Botswana, Division of Pediatric Infectious Diseasesand Global Health Center, Department of Pediatrics, Children’s Hospital of Philadelphia, Divisionof Pulmonary, Allergy, and Critical Care Medicine, Duke University, Botswana–UPenn Partnership, Botswana–UPenn Partnership, Cincinnati Children's Hospital Medical Center, Department of Paediatrics &Adolescent Health, University of Botswana and Division of Pediatric Infectious Diseases, Duke University