Tohoku University, Tohoku University, Tohoku University, Tohoku University - Department of Medical Biochemistry, Ritsumeikan University, Ritsumeikan University, Ritsumeikan University, Kumamoto University, Hokkaido University - Division of Global Epidemiology, The University of Osaka, Juntendo University, The University of Osaka, Tohoku University - Frontier Research Institute for Interdisciplinary Sciences and Tohoku University