Imperial College London, NHLI, Imperial College London, NHLI, Imperial College London, Genetic Epidemiology Group, Department of Health Sciences,George Davies Centre, University of Leicester, University of Oulu - Centre for Life Course Health Research, Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, University of Oulu, University of Oulu - Department of Physiology, Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, Imperial College London - National Heart and Lung Institute (NHLI) and Imperial College London - MRC-PHE Centre for Environment and Health