Central South University - Department of Gastroenterology, Zhejiang University, Central South University - Department of Gastroenterology, Zhejiang University - Department of Big Data in Health Science, Poznan University of Medical Sciences, University of Edinburgh, KU Leuven, Karolinska Institutet - Unit of Cardiovascular and Nutritional Epidemiology, University of Oxford - John Radcliffe Hospital, University of Edinburgh, University of Edinburgh - Western General Hospital, Department of Colorectal Surgery, Örebro University, Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-Sen University, University of Edinburgh - Edinburgh Cancer Research UK Centre, University of Oxford and Zhejiang University - Department of Big Data in Health Science