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Leo A.B. Joosten

Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI)

Nijmegen

Netherlands

Radboud University Nijmegen - Department of Internal Medicine

  • Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI)

SCHOLARLY PAPERS

7

DOWNLOADS

363

TOTAL CITATIONS

4

Scholarly Papers (7)

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1.

The BNT162b2 mRNA Vaccine Against SARS-CoV-2 Reprograms Both Adaptive and Innate Immune Responses

Number of pages: 29 Posted: 04 May 2021
F. Konstantin Föhse, Büsranur Geckin, Gijs J. Overheul, Josephine van de Maat, Gizem Kilic, Ozlem Bulut, Helga Dijkstra, Heidi Lemmers, S. Andrei Sarlea, Maartje Reijnders, Jacobien Hoogerwerf, Jaap ten Oever, Elles Simonetti, Frank L. van de Veerdonk, Leo A.B. Joosten, Bart L. Haagmans, Reinout Van Crevel, Yang Li, Ronald P. van Rij, Corine Geurtsvan Kessel, Marien I. de Jonge, Jorge Domínguez-Andrés and Mihai G. Netea
Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Erasmus Medical Center - Viroscience Department, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Institute for Molecular Life Sciences (RIMLS), Erasmus University Rotterdam (EUR) - Department of Viroscience, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI) and Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI)
Downloads 99 (699,467)
Citation 3

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COVID-19, coronaviruses, mRNA vaccines, trained immunity, innate immune tolerance

2.

Genomic and transcriptomic profiling links autophagy-related SNPs to Borrelia burgdorferi-induced cytokine responses in Lyme borreliosis

Downloads 95 (736,406)

Genomic and transcriptomic profiling links autophagy-related SNPs to Borrelia burgdorferi-induced cytokine responses in Lyme borreliosis

Number of pages: 28 Posted: 29 Sep 2025
Zara Karami, Kathrin Erler, Javier Botey Bataller, Hedwig Vrijmoeth, Mariska Kerstholt, Marije Oosting, Martin Jaeger, Hadewych J.M. ter Hofstede, Yang Li, Mihai G. Netea and Leo A.B. Joosten
affiliation not provided to SSRN, affiliation not provided to SSRN, Helmholtz Centre for Infection Research, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Helmholtz Centre for Infection Research, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI) and Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI)
Downloads 52 (1,072,374)

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Borrelia burgdorferi, Lyme borreliosis, autophagy, transcritomics, genomics

Genomic and transcriptomic profiling links autophagy-related SNPs to Borrelia burgdorferi-induced cytokine responses in Lyme borreliosis

Number of pages: 28 Posted: 08 Jan 2026
Zara Karami, Kathrin Erler, Javier Botey Bataller, Hedwig Vrijmoeth, Mariska Kerstholt, Marije Oosting, Martin Jaeger, Hadewych J.M. ter Hofstede, Yang Li, Mihai G. Netea and Leo A.B. Joosten
affiliation not provided to SSRN, affiliation not provided to SSRN, Helmholtz Centre for Infection Research, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Helmholtz Centre for Infection Research, Radboud University Nijmegen - Radboud Institute for Molecular Life Sciences (RIMLS) and Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI)
Downloads 43 (1,210,354)

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Borrelia burgdorferi, Lyme borreliosis, autophagy, transcritomics, genomics

3.

Persistent Viral Control Status is Associated with Enhanced Innate Immune Responses in People Living with Hiv-1

Number of pages: 37 Posted: 28 Mar 2025
Jéssica Cristina dos Santos, Albert L. Groenendijk, Suzanne D.E. Ruijten, Rainer Knoll, Nadira Vadaq, Rob ter Horst, Ezio Fok, Wojciech Witkowski, Marc J. T. Blaauw, Louise E. van Eekeren, Wilhelm A. J. W. Vos, Maartje Cleophas-Jacobs, Stephan Reichl, Twan Otten, Joost H. A. Martens, Arnold van der Meer, Han Koninkx, Marien I. de Jonge, Marc D. Beyer, Jan van Lunzen, Leo A.B. Joosten, Christoph Bock, Casper Rokx, Annelies Verbon, Linos Vandekerckhove, Anna C. Aschenbrenner, Joachim L. Schultze, Vasiliki Matzaraki, Andre J. A. M. van der Ven, Mihai G. Netea and Sneak Peek Administrator
Radboud University Nijmegen - Radboud University Medical Center, Erasmus University Rotterdam (EUR), Radboud University Nijmegen - Radboud University Medical Center, University of Bonn, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen, Ghent University, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Austrian Academy of Sciences - CeMM Research Center for Molecular Medicine, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, German Center for Neurodegenerative Diseases (DZNE), Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Austrian Academy of Sciences - CeMM Research Center for Molecular Medicine, Erasmus University Rotterdam (EUR), Erasmus University Rotterdam (EUR) - Erasmus Medical Center (MC), Ghent University, German Center for Neurodegenerative Diseases (DZNE) - Systems Medicine, German Center for Neurodegenerative Diseases (DZNE) - Systems Medicine, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI) and Independent
Downloads 51 (1,074,648)

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Spontaneous HIV control, monocytes, trained immunity

4.

Cell-Death Dependent Interleukin-1α Release Activates Host NLRP3 Inflammasome and Promotes Epithelial-Mesenchymal Transition in Metastatic Breast Cancer

Number of pages: 24 Posted: 23 May 2022
Isak W. Tengesdal, Shaikh M. Atif, Makenna May, Douglas G. Mack, Andrew P. Fontenot, Leo A.B. Joosten and Charles A. Dinarello
University of Colorado at Denver - Department of Medicine, University of Colorado, Aurora - Department of Medicine, University of Colorado, Aurora - Department of Medicine, University of Colorado, Aurora - Department of Medicine, University of Colorado, Aurora - Department of Medicine, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI) and University of Colorado at Denver - Department of Medicine
Downloads 36 (1,249,711)

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5.

Hyperuricemia Remodels the Serum Proteome Toward a Higher Inflammatory State

Number of pages: 48 Posted: 29 Jun 2023
Georgiana Cabau, Orsolya Gaal, Medeea Badii, Valentin Nica, Andreea Manuela Mirea, Ioana Hotea, HINT Consortium, Cristina Pamfil, Radu Anghel Popp, Mihai G. Netea, Simona Rednic, Tania Octavia Crisan and Leo A.B. Joosten
Iuliu Hațieganu University of Medicine and Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, Radboud University Nijmegen - Department of Internal Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, Independent, Iuliu Hațieganu University of Medicine and Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Iuliu Hațieganu University of Medicine and Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy and Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI)
Downloads 29 (1,345,526)
Citation 1

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gout, Hyperuricemia, proteomics, Inflammation, FGF21

6.

Single High-Fat Challenge and Trained Innate Immunity: A Randomized Controlled Cross-Over Trial

Number of pages: 39 Posted: 03 Mar 2024
Julia van Tuijl, Julia I.P. van Heck, Harsh Bahrar, Wieteke Broeders, Johan Wijma, Yvonne M. ten Have, Martin Giera, Heidi Zweers-van Essen, Laura Rodwell, Leo A.B. Joosten, Mihai G. Netea, Lydia A. Afman, Siroon Bekkering and Niels Riksen
Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Leiden University - Center for Proteomics & Metabolomics, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud University Medical Center, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Wageningen University, University of Melbourne - Murdoch Children's Research Institute and Radboud University Nijmegen - Radboud Institute for Molecular Life Sciences (RIMLS)
Downloads 28 (1,372,601)

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7.

Genetic Regulators of Plasma Protein Abundance in a Tanzanian Population: A Comparison with West-European Populations

Number of pages: 40 Posted: 09 Feb 2024
Caroline Amour, Collins K. Boahen, Godfrey S. Temba, Nadira Vadaq, Vesla Kullaya, Blandina T. Mmbaga, Leo A.B. Joosten, Reginald A. Kavishe, Mihai G. Netea, Quirijn de Mast, Vinod Kumar and Sneak Peek Administrator
Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen - Department of Internal Medicine, Kilimanjaro Christian Medical University College, Kilimanjaro Christian Medical University College - Kilimanjaro Clinical Research Institute, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Kilimanjaro Christian Medical University College, Radboud University Nijmegen - Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen - Department of Internal Medicine, Radboud University Nijmegen - Radboud University Medical Center and Independent
Downloads 25 (1,399,036)

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