Zhejiang University - Department of General Surgery, Shaoxing People's Hospital - Department of Gastrointestinal Surgery, Nanjing University - Department of Gastroenterology, Government of the People's Republic of China - Department of Gastrointestinal Surgery, Zhejiang University - Department of General Surgery, Zhejiang University - Key Laboratory of Endoscopic Technique Research of Zhejiang Province, Zhejiang University - Department of General Surgery, Fujian University of Traditional Chinese Medicine - Fujian Key Laboratory of TCM Health State, Shaoxing People's Hospital - Department of Gastrointestinal Surgery, Government of the People's Republic of China - Department of Gastrointestinal Surgery, Government of the People's Republic of China - Department of Gastrointestinal Surgery, Nanjing Medical University - School of Public Health, University of California, Berkeley - Biological Systems and Engineering Division, Nanjing KDRB Biotech Inc., Ltd, Jiangning District, Nanjing University - Department of Gastroenterology and University of California, Berkeley - Biological Systems and Engineering Division