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John N. Mariani

University of Rochester Medical Center - Center for Translational Neuromedicine

United States

  • University of Rochester Medical Center - Center for Translational Neuromedicine

SCHOLARLY PAPERS

3

DOWNLOADS

133

TOTAL CITATIONS

1

Scholarly Papers (3)

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1.

Age-Associated Induction of Senescent Transcriptional Programs in Human Glial Progenitor Cells

Number of pages: 51 Posted: 26 Oct 2021
John N. Mariani, Pernille M. Madsen, Benjamin Mansky, Nguyen P. T. Huynh, Nicholas Kuypers, Erin R. Kesel, Devin Chandler-Militello, Abdellatif Benraiss and Steven Goldman
University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Copenhagen Faculty of Health - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine and University of Rochester Medical Center - Center for Translational Neuromedicine
Downloads 67 (916,100)

Abstract:

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Human glial progenitor cells, aging, Senescence, proliferation, transcription, rejuvenation, RNA-seq, single cell RNA-Seq, miRNA, transcription factor, stem cell exhaustion

2.

Cell-Intrinsic Astrocytic Pathology is Conserved Across Both Species and Models of Huntington Disease

Number of pages: 42 Posted: 27 Aug 2020
Abdellatif Benraiss, John N. Mariani, Mikhail Osipovitch, Adam Cornwell, Martha Windrem, Carlos Benitez Villanueva, Devin Chandler-Militello and Steven Goldman
University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Copenhagen - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine, University of Copenhagen - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine and University of Rochester Medical Center - Center for Translational Neuromedicine
Downloads 42 (1,157,785)

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Huntington's disease, astrocytes, mouse models, human embryonic stem cells, cholesterol, glia, glial transcription

3.

Huntington Disease Mice Exhibit a TCF7L2-Responsive Suppression of Both Homeostatic and Compensatory Remyelination

Number of pages: 39 Posted: 10 Sep 2021
Abdellatif Benraiss, John N. Mariani, Ashley Tate, Renee Solly, Laetitia Capellano, Karen L. de Mesy Bentley, Devin Chandler-Militello and Steven Goldman
University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester Medical Center - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine, University of Rochester - Center for Translational Neuromedicine and University of Rochester Medical Center - Center for Translational Neuromedicine
Downloads 24 (1,399,036)
Citation 1

Abstract:

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Huntington's Disease, myelination, glia, gliogenesis, Oligodendrocyte Progenitor Cell, TCF7L2