Hospital for Sick Children Research Institute - Program in Molecular Medicine, Children’s Hospital of Philadelphia - Division of Oncology, Children’s Hospital of Philadelphia - Division of Oncology, University of Pittsburgh - Department of Medicine, National Cancer Institute - Cancer and Inflammation Program, Hospital for Sick Children Research Institute - Program in Molecular Medicine, University of Pennsylvania - Department of Pathology and Lab Medicine, Children's Hospital of Philadelphia - Department of Pathology, National Cancer Institute - Cancer and Inflammation Program, Children's Hospital of Philadelphia - Division of Oncology, Children's Hospital of Philadelphia - Department of Bioinformatics and Health Informatics, University of Pennsylvania - The Center for Data Driven Discovery in Biomedicine, Integral Molecular, Integral Molecular, Children's Hospital Los Angeles - Department of Pathology and Laboratory Medicine, University of Pittsburgh - Department of Medicine, Children’s Hospital of Philadelphia - Division of Oncology, Hospital for Sick Children Research Institute - Program in Molecular Medicine and Children’s Hospital of Philadelphia - Division of Oncology