Department of Laboratory Medicine, the First People’s Hospital of Yancheng City, Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Department of Gastroenterology, Affiliated Hospital of Nantong University, University of Wisconsin-Madison - Department of Medical Genetics, Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Office of Research Support Services, Marshfield Clinic Research Institute, Department of Pathology, Affiliated Hospital of Nantong University, Fudan University - Ministry of Education Key Laboratory of Contemporary Anthropology, Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Department of Laboratory Medicine, Affiliated Hospital of Nantong University, Fudan University - State Key Laboratory of Genetic Engineering and Nantong University - Department of Laboratory Medicine