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Deon Bezuidenhout

Merck (Pty) Ltd (an affiliate of Merck KGaA, Darmstadt, Germany)

Modderfontein

South Africa

  • Merck (Pty) Ltd (an affiliate of Merck KGaA, Darmstadt, Germany)

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A Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Chemoprophylactic Activity of M5717 Against Plasmodium Falciparum in a Controlled Human Malaria Infection

Number of pages: 36 Posted: 22 Nov 2022
Johan L. van der Plas, Vincent P. Kuiper, Wilhelmina M. Bagchus, Matthias Bödding, Özkan Yalkinoglu, Aliona Tappert, Andrea Seitzinger, Thomas Spangenberg, Deon Bezuidenhout, Justin Wilkins, Claude Oeuvray, Satish K. Dhingra, Vandana Thathy, David A. Fidock, Lisanne C.A. Smidt, Geert V.T. Roozen, Jan Pieter R. Koopman, Olivia A.C. Lamers, Jeroen Sijtsma, Roos van Schuijlenburg, Els Wessels, Pauline Meij, Ingrid M.C. Kamerling, Meta Roestenberg and Akash Khandelwal
Centre for Human Drug Research, Leiden University - Department of Infectious Diseases, Merck Serono S.A. (an affiliate of Merck KGaA, Darmstadt, Germany) - Merck Institute for Pharmacometrics, Merck Healthcare KGaA, Merck Healthcare KGaA, Merck Healthcare KGaA, Merck Healthcare KGaA, Ares Trading S.A. (a subsidiary of Merck KGaA, Darmstadt, Germany) - Global Health Institute of Merck, Merck (Pty) Ltd (an affiliate of Merck KGaA, Darmstadt, Germany), Occams, Ares Trading S.A. (a subsidiary of Merck KGaA, Darmstadt, Germany) - Global Health Institute of Merck, Hemogenyx Pharmaceuticals, Columbia University - Department of Microbiology and Immunology, Columbia University - Department of Microbiology and Immunology, Centre for Human Drug Research, Leiden University - Department of Parasitology, Leiden University - Department of Infectious Diseases, Leiden University - Department of Infectious Diseases, Leiden University - Department of Infectious Diseases, Leiden University - Department of Infectious Diseases, Leiden University - Department of Medical Microbiology, Leiden University - Center for Cell and Gene Therapy, Centre for Human Drug Research, Leiden University - Department of Infectious Diseases and Ares Trading S.A. (a subsidiary of Merck KGaA, Darmstadt, Germany) - Global Health Institute of Merck
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Abstract:

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Adaptive intervention, Chemoprevention, Healthy participants, M5717, Malaria