Harvard University - Cardiovascular Research Institute, National Jewish Health, Helmholtz Association of German Research Centres - German Research Centre for Environmental Health, Lovelace Respiratory Research Institute, University of North Carolina (UNC) at Chapel Hill - Department of Pathology and Laboratory Medicine, University of Virginia - Center for Public Health Genomics, Harvard University - Cardiovascular Research Institute, Harvard University - Cardiovascular Research Institute, Harvard University - Cardiovascular Research Institute, National Jewish Health, Boston University School of Public Health - Department of Biostatistics, AstraZeneca - Translational Science and Experimental Medicine, Helmholtz Association of German Research Centres - German Research Centre for Environmental Health, Weill Cornell Medicine in Qatar - Department of Physiology and Biophysics, Max Planck Institute for Heart and Lung Research - Biomolecular Mass Spectrometry, University of Washington - Department of Biostatistics, University of Washington - Department of Biostatistics, University of Vermont - Department of Pathology and Laboratory Medicine, UCLA Medical Center - The Institute for Translational Genomics and Population Sciences, Duke University - Duke Molecular Physiology Institute, University of Washington - Department of Biostatistics, University of Vermont - Department of Pathology and Laboratory Medicine, University of Vermont - Department of Pathology and Laboratory Medicine, UCLA Medical Center - The Institute for Translational Genomics and Population Sciences, Government of the United States of America - National Heart, Lung and Blood Institute, University of Virginia - Center for Public Health Genomics, UCLA Medical Center - The Institute for Translational Genomics and Population Sciences, University of Nebraska at Omaha, University of Michigan at Ann Arbor, University of California, San Francisco (UCSF) - Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of Iowa, Carver College of Medicine, Department of Internal Medicine, Harvard University - Channing Division of Network Medicine, National Jewish Health, Boston University School of Public Health - Department of Biostatistics, Boston University - Preventive Medicine and Epidemiology, University of Texas Southwestern Medical Center - Department of Medicine, Beth Israel Deaconess Medical Center - Division of Cardiovascular Medicine, Boston University - Chobanian & Avedisian School of Medicine, Columbia University - Irving Medical Center, University of North Carolina (UNC) at Chapel Hill - Department of Biostatistics, Boston University - Department of Biostatistics, University of Virginia - Center for Public Health Genomics, University of North Carolina (UNC) at Chapel Hill, Harvard University - Division of Pulmonary and Critical Care Medicine, Helmholtz Association of German Research Centres - German Research Centre for Environmental Health and National Jewish Health - Department of Medicine