Florian Krammer

Icahn School of Medicine at Mount Sinai - Department of Microbiology

United States

SCHOLARLY PAPERS

16

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765

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23

Scholarly Papers (16)

1.

Intranasal SARS-CoV-2 Omicron Variant Vaccines Elicit Humoral and Cellular Mucosal Immunity in Mice

Number of pages: 36 Posted: 11 Jul 2023
Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, National Institutes of Health - Vaccine Research Center, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, QBI Coronavirus Research Group (QCRG), Icahn School of Medicine at Mount Sinai - Department of Microbiology, Mount Sinai Health System - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology and Mount Sinai School of Medicine - Department of Microbiology
Downloads 224 (272,969)

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COVID-19, mucosal immune response, low cost vaccine platform, variant vaccine, NDV vector, mRNA vaccine, prime-pull vaccination

2.

Universal Antibody Targeting the Highly Conserved Fusion Peptide Induces Antibody-Dependent Cellular Cytotoxicity Against Diverse Strains of Both Influenza Types A and B Viruses

Number of pages: 18 Posted: 31 Jul 2021
University of Ottawa, University of British Columbia, Government of Canada - Health Canada, University of Ottawa, Public Health Agency Canada - National Microbiology Laboratory, Public Health Agency Canada - National Microbiology Laboratory, National Research Council Canada, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Government of Canada - Health Canada, Government of Canada - Health Canada, The Chinese University of Hong Kong (CUHK) - Department of Economics and Government of Canada - Health Canada
Downloads 82 (602,114)

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influenza, universal antibody, Uni-1, antibody-dependent cellular cytotoxicity (ADCC)

3.

Resilient Fc-Effector Functions Across SARS-CoV-2 Variants of Concern Following mRNA-1273 Vaccination

Number of pages: 11 Posted: 23 Apr 2021
Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Harvard University - Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Harvard University - Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Harvard University - Ragon Institute of MGH, MIT and Harvard, Space Exploration Technologies Corp, Space Exploration Technologies Corp, La Jolla Institute for Immunology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Harvard University - Ragon Institute of MGH, MIT and Harvard, Harvard University - Brigham and Women's Hospital, Space Exploration Technologies Corp, Space Exploration Technologies Corp, Icahn School of Medicine at Mount Sinai - Department of Microbiology, La Jolla Institute for Immunology - Center for Infectious Disease and Vaccine Research, Moderna, Inc. and Ragon Institute of MGH, MIT and Harvard
Downloads 57 (725,513)

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4.

Safety and Immunogenicity of an Egg-Based Inactivated Newcastle Disease Virus Vaccine Expressing SARS-CoV-2 Spike: Interim Results of a Randomized, Placebo-Controlled, Phase 1/2 Trial in Vietnam

Number of pages: 28 Posted: 10 Feb 2022
National Institute of Hygiene and Epidemiology, National Institute of Hygiene and Epidemiology, affiliation not provided to SSRN, Hanoi Medical University, Hanoi Medical University, Hanoi Medical University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Mahidol University, Center of Excellence for Biomedical and Public Health Informatics (BIOPHICS), University of Texas at Austin - Department of Molecular Biosciences, affiliation not provided to SSRN, QBI Coronavirus Research Group (QCRG), Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, Mount Sinai School of Medicine - Department of Microbiology, affiliation not provided to SSRN, affiliation not provided to SSRN, Icahn School of Medicine at Mount Sinai - Department of Microbiology, affiliation not provided to SSRN, affiliation not provided to SSRN, PATH, PATH, PATH, PATH, PATH, PATH, PATH, PATH and PATH
Downloads 54 (743,764)

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SARS-CoV-2, COVID-19, Newcastle disease virus, Egg-based vaccine

5.

SARS-CoV-2 Seropositivity and Subsequent Infection Risk in Healthy Young Adults: A Prospective Cohort Study

Number of pages: 28 Posted: 05 Feb 2021
United States Department of the Navy - Naval Medical Research Center - Silver Spring, Icahn School of Medicine at Mount Sinai - Department of Neurology, Icahn School of Medicine at Mount Sinai - Department of Neurology, United States Department of the Navy - Naval Medical Research Center - Silver Spring, Naval Medical Research Center, Silver Spring, University of Texas Medical Branch-Galveston - Department of Pathology, Naval Medical Research Center, Silver Spring, Naval Medical Research Center, Silver Spring, Icahn School of Medicine at Mount Sinai - Department of Neurology, Icahn School of Medicine at Mount Sinai - Department of Neurology, Naval Medical Research Center, Silver Spring, Naval Medical Research Center, Silver Spring, University of Texas Medical Branch-Galveston - Department of Pathology, Naval Medical Research Unit SIX, Naval Medical Research Unit SIX, United States Department of the Navy - Naval Medical Research Center - Silver Spring, Icahn School of Medicine at Mount Sinai - Department of Neurology, Icahn School of Medicine at Mount Sinai - Department of Neurology, Icahn School of Medicine at Mount Sinai - Department of Neurology, Icahn School of Medicine at Mount Sinai - Department of Neurology, Naval Medical Research Center, Silver Spring, University of Vermont - Department of Pathology & Laboratory Medicine, United States Department of the Navy - Naval Medical Research Center - Silver Spring, Naval Medical Research Center, Silver Spring, United States Department of the Navy - Naval Medical Research Center - Silver Spring, Icahn School of Medicine at Mount Sinai - Department of Microbiology, United States Department of the Navy - Naval Medical Research Center - Silver Spring, Naval Medical Readiness and Training Command Beaufort, United States Department of the Navy - Naval Medical Research Center - Silver Spring, University of Vermont - Department of Pathology & Laboratory Medicine, Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Texas Medical Branch-Galveston - Department of Pathology, Icahn School of Medicine at Mount Sinai - Department of Neurology and Icahn School of Medicine at Mount Sinai - Department of Neurology
Downloads 50 (769,145)
Citation 5

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6.

Development and Characterization of a Quantitative ELISA to Detect Anti-SARS-CoV-2 Spike Antibodies

Number of pages: 18 Posted: 08 Sep 2021
Mount Sinai Health System - Cardiovascular Research Institute, Mount Sinai Health System - Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Mount Sinai Health System - Department of Pathology, Molecular and Cell-Based Medicine, Mount Sinai Health System - Department of Neuroscience, Mount Sinai Health System - Department of Oncological Sciences, Mount Sinai Health System - Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Mount Sinai Health System - Department of Pathology, Molecular and Cell-Based Medicine, Mount Sinai Health System - Department of Pathology, Molecular and Cell-based Medicine, Icahn School of Medicine at Mount Sinai - Department of Microbiology and Mount Sinai Health System - Department of Pathology, Molecular and Cell-Based Medicine
Downloads 46 (796,430)

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coronavirus disease 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), antibody tests, diagnosis of COVID-19, ELISA, IgG antibody assay

7.

Re: Integrated Immune Dynamics Define Correlates of COVID-19 Severity and Antibody Responses

Number of pages: 56 Posted: 13 Oct 2020
University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), The University of Sydney - Sydney Cytometry Core Research Facility, The University of Sydney - Charles Perkins Centre, The University of Sydney - Charles Perkins Centre, The University of Sydney - School of Computer Science, The University of Sydney - School of Computer Science, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Melbourne - Peter Doherty Institute for Infection and Immunity, The Austin Hospital - Department of Infectious Diseases, Monash Medical Centre - Monash Infectious Diseases, Peter Doherty Institute for Infection and Immunity - Victorian Infectious Diseases Reference Laboratory, University of Melbourne - Peter Doherty Institute for Infection and Immunity, University of Melbourne - Peter Doherty Institute for Infection and Immunity, QIMR Berghofer Medical Research Institute - Infectious Diseases Programme, Monash University - Respiratory Medicine Laboratory, University of Melbourne - Department of Microbiology and Immunology (DMI), Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Peter Doherty Institute for Infection and Immunity, The University of Sydney - Sydney Cytometry Core Research Facility, University of Melbourne - Peter Doherty Institute for Infection and Immunity, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - WHO Collaborating Centre for Reference and Research on Influenza, Monash University - Department of Infectious Diseases, University of Melbourne - Peter Doherty Institute for Infection and Immunity, University of Melbourne - Department of Microbiology and Immunology (DMI), Monash University - Department of Infectious Diseases and University of Melbourne - Department of Microbiology and Immunology (DMI)
Downloads 44 (810,733)
Citation 4

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COVID-19, immune correlates, disease severity, IL-6R, hyperactivation

8.

Safety and Immunogenicity of an Inactivated Recombinant Newcastle Disease Virus Vaccine Expressing Sars-Cov-2 Spike: A Randomised, Comparator-Controlled, Phase 2 Trial

Number of pages: 26 Posted: 30 May 2024
National Institute of Hygiene and Epidemiology, National Institute of Hygiene and Epidemiology, National Institute of Hygiene and Epidemiology, affiliation not provided to SSRN, PATH, La Jolla Institute for Immunology, affiliation not provided to SSRN, PATH, PATH, PATH, PATH, La Jolla Institute for Immunology, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, La Jolla Institute for Allergy and Immunology (LIAI) - Division of Vaccine Discovery, PATH, Icahn School of Medicine at Mount Sinai - Department of Microbiology and La Jolla Institute for Immunology
Downloads 34 (890,693)

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SARS-CoV-2, COVID-19, Newcastle disease virus, Egg-based vaccine, Phase II clinical trial

9.

High Precursor Frequency and Promiscuity in Αβ T Cell Receptor Pairing Underpin CD8+ T-Cell Responses to an Immunodominant SARS-CoV-2 Nucleocapsid Epitope

Number of pages: 35 Posted: 19 Dec 2020
University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), Monash University - Infection and Immunity Program, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), Monash University - Infection and Immunity Program, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), Icahn School of Medicine at Mount Sinai - Department of Microbiology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, James Cook University - Centre for Molecular Therapeutics, Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Tasmania - School of Medicine, University of Tasmania - School of Medicine, University of Melbourne - Department of Microbiology and Immunology (DMI), Alfred Hospital - Lung Transplant Unit, Austin Hospital - Department of Infectious Diseases, Austin Hospital - Department of Infectious Diseases, University of Melbourne - Department of Microbiology and Immunology (DMI), The Austin Hospital - Department of Infectious Diseases, Austin Hospital - Department of Infectious Diseases, Monash University - Department of Infectious Diseases, Monash University - Department of Infectious Diseases, AFL House, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), Monash University - Infection and Immunity Program, University of Melbourne - Department of Microbiology and Immunology (DMI) and University of Melbourne - Department of Microbiology and Immunology (DMI)
Downloads 33 (899,406)

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10.

COVID-19 Infection Induces Substantial Memory B Cell Maturation to Non-Neutralizing Viral Targets

Number of pages: 58 Posted: 22 Feb 2021
University of Chicago - Committee on Immunology, University of Chicago - Committee on Immunology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Pritzker School of Molecular Engineering, University of Wisconsin - Madison - Influenza Research Institute, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Committee on Immunology, University of Chicago - Department of Medicine, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Department of Medicine, Washington University in St. Louis - Department of Medicine, University of Chicago - Department of Surgery, University of Chicago - Department of Surgery, University of Chicago - Department of Medicine, Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Committee on Immunology, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Division of Immunobiology, University of Chicago - Section of Rheumatology, University of Chicago - Center for Structural Genomics of Infectious Diseases, University of Chicago - Center for Structural Genomics of Infectious Diseases, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Washington University in St. Louis - Department of Medicine, Washington University in St. Louis - Division of Immunobiology, University of Wisconsin - Madison - Influenza Research Institute and University of Chicago - Section of Rheumatology
Downloads 30 (926,717)
Citation 11

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11.

SARS-CoV-2 Infection in Children Does Not Necessitate Establishment of Adaptive SARS- CoV-2-Specific Immunological Memory

Number of pages: 49 Posted: 04 Nov 2021
University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Infection and Immunity, Monash University - Infection and Immunity Program and Department of Biochemistry and Molecular Biology, St Jude Children’s Research Hospital - Department of Immunology, University of Melbourne - Department of Microbiology and Immunology, St. Jude Children's Research Hospital - Department of Immunology, St. Jude Children's Research Hospital - Department of Immunology, Monash University - Infection and Immunity Program, University of Melbourne - Department of Microbiology and Immunology, University of Melbourne - Department of Microbiology and Immunology (DMI), University of Melbourne - Department of Microbiology and Immunology, University of Melbourne - Department of Microbiology and Immunology (DMI), Icahn School of Medicine at Mount Sinai - Department of Microbiology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Tasmania - School of Medicine, University of Tasmania - School of Health Sciences and School of Medicine, University of Melbourne - Infection and Immunity, University of Melbourne - Department of Microbiology and Immunology (DMI), Monash University - Infection and Immunity Program, St Jude Children’s Research Hospital - Department of Immunology, University of Melbourne - Department of General Medicine, University of Melbourne - Infection and Immunity, University of Melbourne - Department of Microbiology and Immunology (DMI) and University of Melbourne - Department of Microbiology and Immunology (DMI)
Downloads 23 (996,818)
Citation 2

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COVID-19, T cells, B cells, seroconversion, children, memory T cells

12.

Co-Administration of Seasonal Quadrivalent Influenza and Covid-19 Vaccines Leads to Enhanced Immune Responses to Influenza Virus and Reduced Immune Responses to Sars-Cov-2 in Naive Mice

Number of pages: 22 Posted: 06 Nov 2024
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Mount Sinai School of Medicine - Department of Microbiology, affiliation not provided to SSRN, University of Liverpool - Institute of Infection Biology and Microbiomes, University of Pennsylvania, University of Pennsylvania, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Pennsylvania, Icahn School of Medicine at Mount Sinai - Department of Microbiology and Icahn School of Medicine at Mount Sinai - Department of Microbiology
Downloads 22 (1,018,608)

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SARS-CoV-2, influenza virus, vaccine co-administration, vaccine immunogenicity, mRNA vaccine, binding antibodies, neutralizing antibodies

13.

Proteomic Signatures of Vaccine-Induced and Breakthrough Infection-Induced Host Responses to Sars-Cov-2

Number of pages: 29 Posted: 13 Sep 2024
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Icahn School of Medicine at Mount Sinai - Department of Microbiology, affiliation not provided to SSRN, University of Miami - Miami Center for AIDS Research and University of Miami - Miami Center for AIDS Research
Downloads 18 (1,052,549)

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SARS-CoV-2, Proteomics, vaccination

14.

Collaboration between the Fab and Fc Contribute to Maximal Protection Against SARS-CoV-2 Following NVX-CoV2373 Subunit Vaccine with Matrix-M™ Vaccination

Number of pages: 41 Posted: 06 Apr 2021
Ragon Institute of MGH, MIT and Harvard, Novavax, Inc., Novavax, Inc., Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Massachusetts Institute of Technology - Department of Biological Engineering, Ragon Institute of MGH, MIT and Harvard, Texas Biomedical Research Institute, Texas Biomedical Research Institute, Novavax, Inc., Ragon Institute of MGH, MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, Novavax, Inc., Novavax, Inc., University of Maryland - School of Medicine, University of Maryland - School of Medicine, University of Maryland - School of Medicine, Duke University - Duke Human Vaccine Institute, La Jolla Institute for Immunology, La Jolla Institute for Immunology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, La Jolla Institute for Immunology - Center for Infectious Disease and Vaccine Research, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Novavax, Inc., Novavax, Inc., Novavax, Inc., Novavax, Inc., Novavax, Inc., Novavax, Inc. and MassachusettsGeneral Hospital - Ragon Institute of MGH, MIT and Harvard
Downloads 18 (1,052,549)
Citation 1

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NVX-CoV2373 vaccine, Matrix-M™ adjuvant, SARS-CoV-2 spike glycoprotein, non-human primate, COVID-19

15.

Integration of Transcriptome and Cell Surface Protein Expression by LinQ-View Identifies Unique Immune Subpopulations

Number of pages: 108 Posted: 03 Mar 2021
University of Chicago - Section of Rheumatology, University of Chicago - Committee on Immunology, University of Chicago - Committee on Immunology, University of Chicago - Committee on Immunology, University of Chicago - Pritzker School of Molecular Engineering, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Department of Surgery, University of Chicago - Department of Surgery, University of Chicago - Section of Hospital Medicine, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Department of Medicine, Washington University in St. Louis - Department of Pathology and Immunology, University of Chicago - Center for Structural Genomics of Infectious Diseases, Washington University in St. Louis - Division of Immunobiology, University of Chicago - Center for Structural Genomics of Infectious Diseases, Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Chicago - Pritzker School of Molecular Engineering, University of Chicago - Department of Pathology and University of Chicago - Section of Rheumatology
Downloads 17 (1,064,005)

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16.

Broadly Neutralizing Antibodies Against Conserved Epitopes of the Hemagglutinin Head are Robustly Recalled by a Novel H1N1 Virus

Number of pages: 60 Posted: 24 Nov 2020
University of Chicago - Section of Rheumatology, The Scripps Research Institute - Department of Integrative Structural and Computational Biology, University of Chicago - Section of Rheumatology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, University of Chicago - Section of Rheumatology, University of Chicago - Committee on Immunology, University of Chicago - Committee on Immunology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, University of Chicago - Section of Rheumatology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, Icahn School of Medicine at Mount Sinai - Department of Microbiology, The Scripps Research Institute - Department of Integrative Structural and Computational Biology and University of Chicago - Section of Rheumatology
Downloads 13 (1,110,963)

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H1N1; hemagglutinin head; lateral patch; receptor-binding site; broadly neutralizing antibodies