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University of Oxford - Oxford Vaccine Group, University of Oxford - Big Data Institute, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Cambridge, University of Oxford - Oxford Vaccine Group, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Cambridge - Department of Medicine, University of Oxford - Big Data Institute, University of Oxford - The Jenner Institute, Public Health England - National Infection Service, University of Oxford - Centre for Vaccinology and Tropical Medicine, Liverpool School of Tropical Medicine - Department of Clinical Sciences, UK Biocentre, University of Sheffield - Department of Infection, Immunity and Cardiovascular Disease, University of Oxford - Oxford Vaccine Group, University of Oxford - Jenner Institute, Newcastle upon Tyne Hospitals NHS Foundation Trust - Department of Infection and Tropical Medicine, GSK plc, University of Oxford - The Jenner Institute, University of Southampton - NIHR Southampton Clinical Research Facility and Biomedical Research Centre, University of Liverpool - School of Tropical Medicine, University of Oxford - Oxford Vaccine Group, University of Bristol - Bristol Vaccine Centre, University of Oxford - The Jenner Institute, University of Oxford - Jenner Institute, St George’s University London - St George’s Vaccine Institute, University College London - Department of Infection, University of Oxford - Clinical BioManufacturing Facility, University Hospitals Birmingham NHS Foundation Trust, University of Oxford - Oxford Vaccine Group, Public Health England - National Infection Service, University of London - Institute of Infection and Immunity, Queen Elizabeth University Hospital, Liverpool School of Tropical Medicine - Department of Clinical Sciences, University of Oxford - The Jenner Institute, University of Oxford - Centre for Vaccinology and Tropical Medicine, University Hospitals Bristol - University Hospitals Bristol and Weston NHS Foundation Trust, University College London, Hull University Teaching Hospitals NHS Trust, Genomics England, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Oxford - The Jenner Institute, London Northwest University Healthcare, University of Oxford - Oxford Vaccine Group, University of Oxford - Oxford Vaccine Group, University of Oxford - Oxford Vaccine Group, Imperial College London - Department of Infectious Disease, University of Oxford - Oxford Vaccine Group, University of Glasgow - College of Medical, Veterinary & Life Sciences, University of Oxford - Centre for Vaccinology and Tropical Medicine, University of Oxford - Centre for Vaccinology and Tropical Medicine, Western General Hospital - Clinical Infection Research Group, MRC-University of Glasgow Centre for Virus Research, Royal Papworth HospitalUniversity of Cambridge - Heart and Lung Research Institute, Nottingham University Hospitals NHS Trust, AstraZeneca Biopharmaceuticals, AstraZeneca Pharmaceuticals, Anuerin Bevan University Health Board, University of Oxford - The Jenner Institute, University of Oxford - The Jenner Institute, University of Oxford - Chinese Academy of Medical Science Oxford Institute (COI), University of Oxford - Oxford Vaccine Group, University of Oxford - Oxford Vaccine Group, University of Oxford - Oxford Vaccine Group, Independent and Independent

University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Clinical Immunology Service, University Hospitals Birmingham NHS Foundation Trust, Harborne Medical Practice, Public Health England, Public Health England - Immunisation and Countermeasures Division, Public Health England - National Infection Service, University of Birmingham - Institute of Cancer and Genomic Sciences and University of Birmingham - Institute of Immunology and Immunotherapy

University Hospitals Bristol - University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, University Hospitals Bristol, Cardiff University - Centre for Trials Research, University of Bristol - Bristol Vaccine Centre, University Hospitals Bristol, Government of the United Kingdom - Royal United Hospitals Bath NHS Foundation Trust, Government of the United Kingdom - National Health Service (NHS), Government of the United Kingdom - Royal United Hospitals Bath NHS Foundation Trust, Public Health England - National Infection Service, University of Bristol, University of Bristol, University of Bristol, University of Bristol, National Health Service, United Kingdom, University College London, University Hospitals Bristol - University Hospitals Bristol and Weston NHS Foundation Trust, University Hospitals Bristol - University Hospitals Bristol NHS Foundation Trust, Government of the United Kingdom - National Health Service (NHS), Government of the United Kingdom - National Health Service (NHS), Government of the United Kingdom - Great Western Hospitals, The Alverton Practice, University of Bristol, University of Bristol, University of Oxford - Centre for Vaccinology and Tropical Medicine, Government of the United Kingdom - National Health Service (NHS), Government of the United Kingdom - National Health Service (NHS), University of Nottingham - Division of Epidemiology and Public Health, University of Bristol - Bristol Vaccine Centre, University of Bristol and Independent

University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Institute of Immunology and Immunotherapy, University of Birmingham - Clinical Immunology Service, University of Birmingham - Institute of Immunology and Immunotherapy, Quinton and Harborne PCN, University of Birmingham - Institute of Immunology and Immunotherapy, Deparment of Buisness Energy and Industrial Strategy - Vaccine Taskforce, Public Health England, Public Health England - Immunisation and Countermeasures Division, Public Health England - National Infection Service, Government of the United Kingdom - National Infection Service, Government of the United Kingdom - National Infection Service, Government of the United Kingdom - National Infection Service, Government of the United Kingdom - National Infection Service, Government of the United Kingdom - National Infection Service, Public Health England, UK Health Security Agency - Rare & Imported Pathogens Laboratory, Government of the United Kingdom - National Infection Service, Government of the United Kingdom - National Infection Service, Public Health England - National Infection Service, Oxford Immunotec LTD, University of Birmingham - Institute of Cancer and Genomic Sciences and University of Birmingham - Institute of Immunology and Immunotherapy

University of London, St. George's, Paediatric Infectious Diseases Research Group, Public Health England Colindale, Public Health England - National Infection Service, affiliation not provided to SSRN, University of Southampton, affiliation not provided to SSRN, London School of Hygiene & Tropical Medicine - Department of Infectious Disease and Epidemiology, University of Oxford - Centre for Vaccinology and Tropical Medicine and University of London - Institute of Infection and Immunity