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Sharon Cantor

University of Massachusetts Worcester - Department of Molecular, Cell and Cancer Biology

55 N Lake Avenue

Worcester, MA 01605

United States

  • University of Massachusetts Worcester - Department of Molecular, Cell and Cancer Biology

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Scholarly Papers (1)

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Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1-Deficient Cells by Increasing DNA Replication Stress

Number of pages: 69 Posted: 20 Oct 2020
Mariana Paes Dias, Vivek Tripathi, Ingrid van der Heijden, Ke Cong, Eleni-Maria Manolika, Panagiotis Galanos, Ewa Gogola, Stefano Annunziato, Cor Lieftink, Miguel Andújar-Sánchez, Marieke van de Ven, Sanjiban Chakrabarty, Roderick L. Beijersbergen, Jirina Bartkova, Sven Rottenberg, Sharon Cantor, Jiri Bartek, Arnab Ray Chaudhuri and Jos Jonkers
Netherlands Cancer Institute - Division of Molecular Pathology, Erasmus Medical Center - Department of Molecular Genetics, Netherlands Cancer Institute - Division of Molecular Pathology, University of Massachusetts Worcester - Department of Molecular, Cell and Cancer Biology, Erasmus Medical Center - Department of Molecular Genetics, Danish Cancer Society Research Centre - Genome Integrity Unit, Netherlands Cancer Institute - Division of Molecular Pathology, Netherlands Cancer Institute - Division of Molecular Pathology, Netherlands Cancer Institute - Division of Molecular Carcinogenesis, Complejo Hospitalario Universitario Insular-Materno Infantil, Netherlands Cancer Institute - Mouse Clinic for Cancer and Aging (MCCA), Manipal Academy of Higher Education (MAHE) - Department of Cell and Molecular Biology, Netherlands Cancer Institute - Division of Molecular Carcinogenesis, Danish Cancer Society Research Centre - Genome Integrity Unit, Netherlands Cancer Institute - Division of Molecular Pathology, University of Massachusetts Worcester - Department of Molecular, Cell and Cancer Biology, Danish Cancer Society Research Centre - Genome Integrity Unit, Erasmus Medical Center - Department of Molecular Genetics and Netherlands Cancer Institute - Division of Molecular Pathology
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Abstract:

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PARP inhibitor, DNA Ligase III, BRCA1, drug resistance, replication stress, ssDNA