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Elsa Sanchez-Lopez

University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction

Assistant Professor

9452 Medical Center Dr.

Altman Clinical and Translational Research Institu

San Diego, CA La Jolla 92093

United States

SCHOLARLY PAPERS

3

DOWNLOADS

183

TOTAL CITATIONS

4

Scholarly Papers (3)

1.

Short Term Metformin Intervention Inhibits IL-6 and IL-1β Secretion and Prevents Acute Respiratory Distress Syndrome-Implications for COVID-19

Number of pages: 59 Posted: 23 Oct 2020
University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, Cedars Sinai Medical Center - Departments of Pediatrics and Biomedical Sciences, Cedars Sinai Medical Center - Departments of Pediatrics and Biomedical Sciences, Janssen Research & Development - CVM Discovery, Janssen Research & Development - CVM Discovery, The Scripps Research Institute - Neuroscience Translational Center, The Scripps Research Institute - Neuroscience Translational Center, The Scripps Research Institute - Neuroscience Translational Center, Janssen Research & Development - CVM Discovery, Cedars Sinai Medical Center - Departments of Pediatrics and Biomedical Sciences, University of California, San Diego (UCSD) - Department of Pharmacology and University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction
Downloads 78 (823,616)
Citation 1

Abstract:

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ARDS, COVID-19, IL-1β, IL-6, mitochondrial DNA, metformin, NLRP3 inflammasome, Spike protein

2.

FEN1-Generated Oxidized DNA Fragments Escape Mitochondria via mPTP- and VDAC-Dependent Channels to License NLRP3 Inflammasome and STING Activation

Number of pages: 69 Posted: 31 Jan 2022
University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, Salk Institute for Biological Studies and University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction
Downloads 72 (867,774)
Citation 2

Abstract:

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cGAS-STING, FEN1, mitochondria, mPTP, mtDNA, NLRP3 inflammasome, OGG1, Ox-mtDNA, VDAC

3.

Monosodium Urate Crystals Regulate a Unique JNK-Dependent Macrophage Metabolic and Inflammatory Response

Number of pages: 45 Posted: 08 Jun 2021
University of California, San Diego (UCSD) - Department of Cellular & Molecular Medicine, UCSD School of Medicine - Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine - Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine - Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine - Division of Rheumatology, Allergy and Immunology, University of California, San Diego (UCSD) - Department of Cellular & Molecular Medicine, University of California, San Diego (UCSD) - Department of Cellular & Molecular Medicine, UCSD School of Medicine - Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine - Division of Rheumatology, Allergy and Immunology, University of California, San Diego (UCSD) - Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego (UCSD) - Department of Cellular & Molecular Medicine and University of California, San Diego (UCSD) - Department of Cellular & Molecular Medicine
Downloads 33 (1,290,922)
Citation 1

Abstract:

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