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Keith L. Ligon

The Broad Institute

415 Main Street

Cambridge, MA 02142

United States

SCHOLARLY PAPERS

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Scholarly Papers (1)

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Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation

Number of pages: 42 Posted: 27 Oct 2020
Evelyne Naus, Youlia Lampi, Jarne Pauwels, Tobias Langenberg, Filip Claes, Jie Xu, Veerle Haemels, Zeynep Kalender Atak, Rob van der Kant, Joost van Durme, Greet De Baets, Keith L. Ligon, Mark Fiers, Kris Gevaert, Stein Aerts, Frederic Rousseau, Joost Schymkowitz and F De Smet
KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, VIB-UGent Center for Medical Biotechnology, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, KU Leuven - Laboratory for Precision Cancer Medicine, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, The Broad Institute, KU Leuven - VIB Center for Brain and Disease, VIB-UGent Center for Medical Biotechnology, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease, KU Leuven - VIB Center for Brain and Disease and KU Leuven - Laboratory for Precision Cancer Medicine
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Abstract:

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cancer, protein aggregation, p53, heat shock response, small molecule