University of Toronto - Department of Pediatrics, University of Toronto - Department of Pediatrics, University of Toronto - Department of Pediatrics, University of Toronto - Dalla Lana School of Public Health, Telethon Kids Institute - Children's Lung Health, Intermountain Healthcare - Department of Precision Genomics, McMaster University - Department of Medicine, McMaster University - Department of Medicine, University of Manitoba - Department of Pediatrics & Child Health, University of Manitoba - Department of Pediatrics & Child Health, University of British Columbia (UBC) - Department of Medicine, University of Manitoba - Department of Pediatrics & Child Health, University of Alberta - Department of Pediatrics, University of British Columbia (UBC) - BC Children's Hospital, Curtin University - School of Physiotherapy and Exercise Science, University of Toronto - Department of Pediatrics, McMaster University - Department of Medicine and University of Toronto - Department of Pediatrics