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Javier Martinez

Medical University of Vienna - Max Perutz Labs

Austria

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Scholarly Papers (1)

1.

The Oxidoreductase PYROXD1 Utilizes NAD(P)+ As an Antioxidant to Sustain tRNA Ligase Activity in Pre-tRNA Splicing and Unfolded Protein Response

Number of pages: 74 Posted: 13 Nov 2020
Medical University of Vienna - Max Perutz Labs, Graz University of Technology - Institute of Biochemistry, University of Zurich - Department of Biochemistry, Medical University of Vienna - Max Perutz Labs, Vienna BioCenter (VBC) - Research Institute of Molecular Pathology, Vienna BioCenter (VBC) - Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), University of Belgrade - Department of Pharmaceutical Chemistry, University of Vienna - Max Perutz Labs, Vienna BioCenter (VBC) - Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC) - Research Institute of Molecular Pathology, University of Tartu - Institute of Molecular and Cell Biology, Vienna BioCenter Core Facilities, Vienna BioCenter (VBC) - Research Institute of Molecular Pathology, University of Belgrade - Department of Pharmaceutical Chemistry, Vienna BioCenter (VBC) - Research Institute of Molecular Pathology, University of Zurich - Department of Biochemistry, University of Vienna - Max Perutz Labs, University of Vienna - Research Institute of Molecular Pathology, Vienna BioCenter (VBC) - Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Graz University of Technology - Institute of Biochemistry, Medical University of Vienna - Max Perutz Labs and Medical University of Vienna - Max Perutz Labs
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Abstract:

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PYROXD1, oxidoreductase, myopathy, tRNA ligase complex, RTCB, oxidative stress, metalloenzyme, copper, NADP+, UPR, pre-tRNA splicing.