State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Dongguan People's Hospital - Department of Critical Care Medicine, School of Medicine, Sun Yat-Sen University, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, School of Medicine, Sun Yat-Sen University, Department of Critical Care Medicine, Dongguan Institute of Respiratory and Critical Care Medicine, Dongguan People's Hospital, Department of Critical Care Medicine, Dongguan Institute of Respiratory and Critical Care Medicine, Dongguan People's Hospital, Department of Critical Care Medicine, Dongguan Institute of Respiratory and Critical Care Medicine, Dongguan People's Hospital, School of Medicine, Sun Yat-Sen University, School of Medicine, Sun Yat-Sen University, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Department of Critical Care Medicine, Dongguan Institute of Respiratory and Critical Care Medicine, Dongguan People's Hospital, Department of Critical Care Medicine, Dongguan Institute of Respiratory and Critical Care Medicine, Dongguan People's Hospital, Novogene Bioinformatics Technology Co., Ltd., Novogene Bioinformatics Technology Co., Ltd., School of Medicine, Sun Yat-Sen University, The University of Sydney - Marie Bashir Institute for Infectious Diseases and Biosecurity, Guangzhou Medical University - State Key Laboratory of Respiratory Diseases, Sun Yat-sen University (SYSU) - School of Medicine and Guangzhou Medical University - Guangzhou Institute of Respiratory Health